E2F1 binds the RRM2 gene promoter

Stable Identifier
R-HSA-8961972
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
E2F1 binds the RRM2 gene promoter
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
E2F1 binds to E2F binding sites in the promoter of the RRM2 gene, encoding Ribonucleoside-diphosphate reductase subunit M2 (DeGregori et al. 1995, Giangrande et al. 2004).
Literature References
PubMed ID Title Journal Year
15014447 Combinatorial gene control involving E2F and E Box family members

Giangrande, PH, Zhu, W, Rempel, RE, Laakso, N, Nevins, JR

EMBO J. 2004
7623816 Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

DeGregori, J, Kowalik, T, Nevins, JR

Mol Cell Biol 1995
Participants
Input
Output
Participates
as an event of
Inferred From
E2f1 binds the Rrm2 gene promoter (Mus musculus)
Authored
Gopinathrao, G  (2004-06-16)
Reviewed
Bosco, G  (2004-06-16)
Created
Orlic-Milacic, M  (2017-02-07)
Cite Us!