CDC45 gene expression is stimulated by E2F1

Stable Identifier
R-HSA-8961915
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
nucleoplasm
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CDC45 gene expression is stimulated by E2F1
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E2F1 directly stimulates transcription of the CDC45 gene (Arata et al. 2000), encoding Cell division control protein 45 homolog, which is required for initiation of DNA replication.

Literature References
PubMed ID Title Journal Year
10692433 Cdk2-dependent and -independent pathways in E2F-mediated S phase induction

Kijima, S, Ohtani, K, Fujita, M, Arata, Y, Kato, JY

J Biol Chem 2000
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
E2F1:TFDP1,TFDP2:CDC45 gene [nucleoplasm] (Homo sapiens)
Active Unit
E2F1:TFDP1,TFDP2 [nucleoplasm]
Authored
Gopinathrao, G  (2004-06-16)
Reviewed
Bosco, G  (2004-06-16)
Created
Orlic-Milacic, M  (2017-02-06)
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