E2F1 directly stimulates transcription of the PCNA gene, which encodes the proliferating cell nuclear antigen, a component of the DNA polymerase complex involved in eukaryotic DNA replication (DeGregori et al. 1995, Li et al. 2003).The PCNA gene transcription is directly repressed by the DREAM complex (Litovchick et al. 2007).
Nevins, JR, DeGregori, J, Kowalik, T
O'Farrell, PH, Duronio, RJ
Lu, CD, Li, YY, Wang, L
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