PCNA gene expression is stimulated by E2F1 and repressed by the DREAM complex

Stable Identifier
R-HSA-8961665
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
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PCNA gene expression is stimulated by E2F1 and repressed by the DREAM complex
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E2F1 directly stimulates transcription of the PCNA gene, which encodes the proliferating cell nuclear antigen, a component of the DNA polymerase complex involved in eukaryotic DNA replication (DeGregori et al. 1995, Li et al. 2003).
The PCNA gene transcription is directly repressed by the DREAM complex (Litovchick et al. 2007).

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hasEvent
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Authored
Gopinathrao, G  (2004-06-16)
Reviewed
Bosco, G  (2004-06-16)
MacPherson, D  (2011-08-25)
Created
Orlic-Milacic, M  (2017-02-03)