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p-MELTF [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-8957070
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
MELTF, fullName evidence="8"Melanotransferrin, TRFM_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Post-translational protein phosphorylation (Homo sapiens)
FAM20C phosphorylates FAM20C substrates (Homo sapiens)
FAM20C:Phosphorylated FAM20C substrates [endoplasmic reticulum lumen] (Homo sapiens)
FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)
p-MELTF [endoplasmic reticulum lumen] (Homo sapiens)
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) (Homo sapiens)
FAM20C phosphorylates FAM20C substrates (Homo sapiens)
FAM20C:Phosphorylated FAM20C substrates [endoplasmic reticulum lumen] (Homo sapiens)
FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)
p-MELTF [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P08582 MELTF
Gene Names
MELTF, MAP97, MFI2
Chain
signal peptide:1-19, chain:20-709, propeptide:710-738
Reference Genes
BioGPS Gene:4241 MELTF
COSMIC (genes):MELTF MELTF
CTD Gene:4241 MELTF
dbSNP Gene:4241 MELTF
ENSEMBL:ENSG00000163975 MELTF
ENSEMBL_homo_sapiens_GENE:ENSG00000163975.14 MELTF
HGNC:7037 MELTF
KEGG Gene (Homo sapiens):4241 MELTF
Monarch:4241 MELTF
NCBI Gene:4241 MELTF
OMIM:155750 MELTF
UCSC:P08582 MELTF
Reference Transcript
RefSeq:NM_033316.3 MELTF
RefSeq:NM_005929.5 MELTF
Other Identifiers
11731100_a_at
11731101_at
11736414_a_at
11736415_at
16963428
220043_PM_s_at
220043_s_at
223723_PM_at
223723_at
235911_PM_at
235911_at
2713141
2713142
2713143
2713144
2713145
2713146
2713147
2713149
2713150
2713151
2713152
2713153
2713155
2713156
2713158
2713159
2713160
2713162
2713163
2713165
2713167
2713169
2713177
2713178
2713179
4241
8093171
85279_at
939_at
A_23_P212042
A_23_P386320
GE62361
GO:0005506
GO:0005515
GO:0005576
GO:0005615
GO:0005768
GO:0005769
GO:0005783
GO:0005788
GO:0005886
GO:0006811
GO:0006826
GO:0007155
GO:0009986
GO:0010756
GO:0016020
GO:0030198
GO:0031410
GO:0043226
GO:0046872
GO:0051604
GO:0055037
GO:0070062
GO:0090091
GO:0098552
GO:1900025
HMNXSV003007302
HMNXSV003015248
HMNXSV003051470
Hs.184727.0.A1_3p_at
ILMN_1672876
ILMN_1809146
ILMN_1811478
ILMN_2259818
PH_hs_0023245
TC03002173.hg
TC03003303.hg
g12804858_3p_at
g5729923_3p_s_at
Participates
as a member of
FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
cleaved GPI-MELTF [extracellular region]
GPI-MELTF [plasma membrane]
MELTF [endoplasmic reticulum lumen]
Inferred To
phospho-Tsf3 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
phospho-p-MELTF [endoplasmic reticulum lumen]
(Drosophila melanogaster)
phospho-p-MELTF [endoplasmic reticulum lumen]
(Gallus gallus)
phospho-p-MELTF [endoplasmic reticulum lumen]
(Mus musculus)
Homologues of p-MELTF [endoplasmic reticulum lumen]
(Drosophila melanogaster)
phospho-MELTF [endoplasmic reticulum lumen]
(Bos taurus)
phospho-MELTF [endoplasmic reticulum lumen]
(Canis familiaris)
phospho-MELTF [endoplasmic reticulum lumen]
(Sus scrofa)
phospho-Meltf [endoplasmic reticulum lumen]
(Rattus norvegicus)
phospho-Tsf1 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
Modified Residues
Name
phosphorylated residue at unknown position
PsiMod Name
phosphorylated residue [MOD:00696]
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with a phosphate group.
Cross References
RefSeq
NP_005920.2
,
NP_201573.1
OpenTargets
ENSG00000163975
GeneCards
P08582
HPA
ENSG00000163975-MELTF
Ensembl
ENSP00000296351
,
ENSG00000163975
,
ENSP00000296350
,
ENST00000296351
,
ENST00000296350
PRO
P08582
Pharos - Targets
P08582
HMDB Protein
HMDBP08698
PDB
6XR0
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.547
7
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