Reactome | p-FGA [endoplasmic reticulum lumen]

p-FGA [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-8957043

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

FGA, Fibrinogen alpha chain component recommendedName: Fibrinopeptide A /component component recommendedName: Fibrinogen alpha chain /component, FIBA_HUMAN

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External Reference Information

External Reference

UniProt:P02671 FGA

Gene Names

FGA

Chain

signal peptide:1-19, peptide:20-35, chain:36-866

Reference Genes

COSMIC (genes):FGA FGA

dbSNP Gene:2243 FGA

ENSEMBL:ENSG00000171560 FGA

Participates

as a member of

FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

FGA(20-866) [platelet alpha granule lumen]

Variant fibrinogen alpha chain [extracellular region]

FGA(20-866) [extracellular region]

FGA [plasma membrane]

FGA [endoplasmic reticulum lumen]

FGA(20-35) [extracellular region]

FGA [extracellular region]

Inferred To

phospho-FGA [endoplasmic reticulum lumen] (Bos taurus)

phospho-FGA [endoplasmic reticulum lumen] (Canis familiaris)

phospho-FGA [endoplasmic reticulum lumen] (Sus scrofa)

phospho-p-FGA [endoplasmic reticulum lumen] (Gallus gallus)

phospho-p-FGA [endoplasmic reticulum lumen] (Mus musculus)

phospho-p-FGA [endoplasmic reticulum lumen] (Rattus norvegicus)

phospho-fga [endoplasmic reticulum lumen] (Xenopus tropicalis)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P02679 FGG	5	FGG [extracellular region] (R-HSA-140585) FGG [endoplasmic reticulum lumen] (R-HSA-8956692) p-FGG [endoplasmic reticulum lumen] (R-HSA-8956993) FGG [plasma membrane] (R-HSA-140918) FGG [platelet alpha granule lumen] (R-HSA-140922)	0.852	11
UniProt:P02675 FGB	5	FGB [extracellular region] (R-HSA-140584) FGB(31-44) [extracellular region] (R-HSA-140876) FGB [plasma membrane] (R-HSA-140917) FGB(31-491) [extracellular region] (R-HSA-140846) FGB(31-491) [platelet alpha granule lumen] (R-HSA-140921)	0.852	11
UniProt:Q8IXL6 FAM20C	1	FAM20C [endoplasmic reticulum lumen] (R-HSA-8952276)	0.623	2
UniProt:P27348 YWHAQ	1	YWHAQ [cytosol] (R-HSA-1445116)	0.564	2
UniProt:P0DTC8 8	2	8 [extracellular region] (R-COV-9755410) 8 [endoplasmic reticulum lumen] (R-COV-9727283)	0.547	2
UniProt:Q99XV0 Q99XV0			0.524	2
UniProt:P02647 APOA1	11	APOA1(25-266) [extracellular region] (R-HSA-174720) APOA1 [endoplasmic reticulum lumen] (R-HSA-8956724) p-APOA1 [endoplasmic reticulum lumen] (R-HSA-8957081) APOA1(25-266) [endocytic vesicle lumen] (R-HSA-2239460) Variant apolipoprotein AI [extracellular region] (R-HSA-976865) APOA1(25-266) [plasma membrane] (R-HSA-216742) APOA1(19-266) [extracellular region] (R-HSA-264771) APOA1(25-267) [endoplasmic reticulum lumen] (R-HSA-174640) APOA1(25-267) [early endosome] (R-HSA-2429641) APOA1(25-267) [cytosol] (R-HSA-2395781) APOA1(25-266) [secretory granule lumen] (R-HSA-350761)	0.483	2

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