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p-PENK [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-8957021
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
PENK, Proenkephalin-A component recommendedName: Synenkephalin /component component recommendedName: Met-enkephalin, PENK_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Post-translational protein phosphorylation (Homo sapiens)
FAM20C phosphorylates FAM20C substrates (Homo sapiens)
FAM20C:Phosphorylated FAM20C substrates [endoplasmic reticulum lumen] (Homo sapiens)
FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)
p-PENK [endoplasmic reticulum lumen] (Homo sapiens)
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) (Homo sapiens)
FAM20C phosphorylates FAM20C substrates (Homo sapiens)
FAM20C:Phosphorylated FAM20C substrates [endoplasmic reticulum lumen] (Homo sapiens)
FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)
p-PENK [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01210 PENK
Gene Names
PENK
Chain
signal peptide:1-24, peptide:25-97, peptide:100-104, peptide:107-111, peptide:114-133, peptide:136-140, peptide:143-183, peptide:186-193, propeptide:196-207, peptide:210-214, propeptide:217-227, peptide:230-234, peptide:237-258, peptide:261-267
Reference Genes
BioGPS Gene:5179 PENK
COSMIC (genes):PENK PENK
CTD Gene:5179 PENK
dbSNP Gene:5179 PENK
ENSEMBL:ENSG00000181195 PENK
HGNC:8831 PENK
KEGG:hsa:5179 PENK
Monarch:5179 PENK
NCBI Gene:5179 PENK
OMIM:131330 PENK
UCSC:P01210 PENK
Reference Transcript
RefSeq:NM_001135690.2 PENK
Other Identifiers
11720425_a_at
11764065_at
213791_PM_at
213791_at
237774_PM_at
237774_at
3136272
3136273
3136274
3136276
3136277
3136278
3136279
3136280
3136281
3136282
3136283
3136284
3136285
3136286
3136293
38291_at
5179
61491_at
8150901
A_23_P417918
A_32_P116285
GE59611
GE632199
GO:0001515
GO:0001649
GO:0001662
GO:0001666
GO:0001964
GO:0002118
GO:0005184
GO:0005576
GO:0005788
GO:0005886
GO:0007165
GO:0007218
GO:0007268
GO:0007600
GO:0007626
GO:0009617
GO:0009636
GO:0014009
GO:0019226
GO:0019233
GO:0023052
GO:0030154
GO:0030424
GO:0030425
GO:0031410
GO:0031628
GO:0032280
GO:0032355
GO:0032496
GO:0034466
GO:0034592
GO:0034599
GO:0035094
GO:0035641
GO:0035902
GO:0038003
GO:0043025
GO:0043204
GO:0043226
GO:0043679
GO:0045471
GO:0048018
GO:0050877
GO:0051592
GO:0051867
GO:0070852
GO:0071305
GO:0071320
GO:0071560
GO:0071871
GO:0098586
GO:0098772
GO:0099013
GO:0099538
GO:2000987
HMNXSV003039784
Hs.104920.0.A1_3p_at
Hs.93557.0.S1_3p_at
ILMN_1726711
J00123_at
PH_hs_0023886
Participates
as a member of
FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
PENK [endoplasmic reticulum lumen]
PENK(210-214) [extracellular region]
PENK(136-140) [extracellular region]
PENK(230-234) [extracellular region]
PENK(100-104) [extracellular region]
PENK(107-111) [extracellular region]
Inferred To
phospho-A0A287ASX7 [endoplasmic reticulum lumen]
(Sus scrofa)
phospho-PENK [endoplasmic reticulum lumen]
(Bos taurus)
phospho-PENK [endoplasmic reticulum lumen]
(Canis familiaris)
phospho-PENK [endoplasmic reticulum lumen]
(Gallus gallus)
phospho-penk [endoplasmic reticulum lumen]
(Xenopus tropicalis)
phospho-Penk [endoplasmic reticulum lumen]
(Mus musculus)
phospho-Penk [endoplasmic reticulum lumen]
(Rattus norvegicus)
Modified Residues
Name
phosphorylated residue at unknown position
PsiMod Name
phosphorylated residue [MOD:00696]
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with a phosphate group.
Cross References
RefSeq
NP_001129162.1
ENSEMBL
ENSP00000324248
,
ENST00000314922
,
ENST00000451791
,
ENSP00000400894
OpenTargets
ENSG00000181195
HPA
ENSG00000181195-PENK
PRO
P01210
Pharos - Targets
P01210
PDB
1PLX
,
1PLW
,
8JGG
,
8JGF
,
5E3A
,
2LWC
,
5E33
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