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p-CDH2 [endoplasmic reticulum lumen]
Stable Identifier
R-HSA-8956899
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen
Synonyms
CDH2, Cadherin-2, CADH2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Post-translational protein phosphorylation (Homo sapiens)
FAM20C phosphorylates FAM20C substrates (Homo sapiens)
FAM20C:Phosphorylated FAM20C substrates [endoplasmic reticulum lumen] (Homo sapiens)
FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)
p-CDH2 [endoplasmic reticulum lumen] (Homo sapiens)
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) (Homo sapiens)
FAM20C phosphorylates FAM20C substrates (Homo sapiens)
FAM20C:Phosphorylated FAM20C substrates [endoplasmic reticulum lumen] (Homo sapiens)
FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)
p-CDH2 [endoplasmic reticulum lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P19022 CDH2
Gene Names
CDH2, CDHN, NCAD
Chain
signal peptide:1-25, propeptide:26-159, chain:160-906
Reference Genes
BioGPS Gene:1000 CDH2
COSMIC (genes):CDH2 CDH2
CTD Gene:1000 CDH2
dbSNP Gene:1000 CDH2
ENSEMBL:ENSG00000170558 CDH2
HGNC:1759 CDH2
KEGG:hsa:1000 CDH2
Monarch:1000 CDH2
NCBI Gene:1000 CDH2
OMIM:114020 CDH2
UCSC:P19022 CDH2
Reference Transcript
RefSeq:NM_001792.4 CDH2
RefSeq:NM_001308176.1 CDH2
Other Identifiers
1000
11726614_at
11726615_a_at
16854434
16854437
203440_PM_at
203440_at
203441_PM_s_at
203441_s_at
2053_at
2054_g_at
3802608
3802612
3802613
3802614
3802615
3802616
3802622
3802623
3802624
3802626
3802627
3802628
3802630
3802631
3802632
3802633
3802634
3802635
3802636
3802637
3802638
3802639
3802641
3802643
3802646
3802661
3802667
3802668
3802669
8022674
A_21_P0009626
A_23_P38732
A_33_P3214159
GE62436
GO:0000902
GO:0003323
GO:0003723
GO:0005509
GO:0005515
GO:0005737
GO:0005788
GO:0005856
GO:0005886
GO:0005911
GO:0005912
GO:0005916
GO:0005925
GO:0007043
GO:0007155
GO:0007156
GO:0007157
GO:0007416
GO:0008013
GO:0009986
GO:0010001
GO:0014032
GO:0014069
GO:0014704
GO:0016020
GO:0016323
GO:0016324
GO:0016327
GO:0016339
GO:0016342
GO:0016477
GO:0019899
GO:0019901
GO:0019903
GO:0021537
GO:0021987
GO:0030027
GO:0030054
GO:0030057
GO:0030154
GO:0030312
GO:0030864
GO:0031012
GO:0034330
GO:0034332
GO:0035995
GO:0042383
GO:0042802
GO:0043005
GO:0043226
GO:0043410
GO:0044331
GO:0044853
GO:0045177
GO:0045202
GO:0045294
GO:0045295
GO:0045296
GO:0046872
GO:0048514
GO:0048787
GO:0048854
GO:0048856
GO:0048870
GO:0048872
GO:0051146
GO:0060019
GO:0060563
GO:0062023
GO:0070161
GO:0070445
GO:0072659
GO:0090090
GO:0090497
GO:0097091
GO:0097118
GO:0097150
GO:0098609
GO:0099634
GO:1902897
GO:2000809
HMNXSV003014953
HMNXSV003056175
ILMN_1779228
PH_hs_0023854
S42303_at
TC18000433.hg
TC18000879.hg
g416292_3p_at
g4502720_3p_a_at
p29752
Participates
as a member of
FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)
Other forms of this molecule
CDH2 [plasma membrane]
CDH2 [endoplasmic reticulum lumen]
Inferred To
phospho-cdh2 [endoplasmic reticulum lumen]
(Xenopus tropicalis)
phospho-CadN2 [endoplasmic reticulum lumen]
(Drosophila melanogaster)
phospho-p-CDH2 [endoplasmic reticulum lumen]
(Gallus gallus)
phospho-p-CDH2 [endoplasmic reticulum lumen]
(Mus musculus)
phospho-p-CDH2 [endoplasmic reticulum lumen]
(Rattus norvegicus)
phospho-CDH2 [endoplasmic reticulum lumen]
(Bos taurus)
phospho-CDH2 [endoplasmic reticulum lumen]
(Canis familiaris)
phospho-CDH2 [endoplasmic reticulum lumen]
(Sus scrofa)
Modified Residues
Name
phosphorylated residue at unknown position
PsiMod Name
phosphorylated residue [MOD:00696]
PsiMod Definition
A protein modification that effectively replaces a hydrogen atom with a phosphate group.
Cross References
RefSeq
NP_001295105.1
,
NP_001783.2
ENSEMBL
ENSP00000382312
,
ENSP00000269141
,
ENST00000269141
,
ENST00000399380
OpenTargets
ENSG00000170558
HPA
ENSG00000170558-CDH2
ZINC - Substances
CADH2_HUMAN
ZINC target
P19022
PRO
P19022
Pharos - Targets
P19022
GlyGen
P19022
ZINC - Predictions - Purchasable
CADH2_HUMAN
HMDB Protein
HMDBP07518
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P35222 CTNNB1
20
CTNNB1 S45A [cytosol]
(R-HSA-9663982)
CTNNB1 S45F [cytosol]
(R-HSA-4791268)
CTNNB1 S45C [cytosol]
(R-HSA-9663983)
CTNNB1 S45Y [cytosol]
(R-HSA-9663975)
CTNNB1 S45N [cytosol]
(R-HSA-9663984)
CTNNB1 S45P [cytosol]
(R-HSA-4791272)
pT41,S45-CTNNB1 S37P [cytosol]
(R-HSA-9663981)
pT41,S45-CTNNB1 S37F [cytosol]
(R-HSA-4839621)
CTNNB1 [nucleoplasm]
(R-HSA-3451168)
CTNNB1 [cytosol]
(R-HSA-448839)
CTNNB1(1-115) [cytosol]
(R-HSA-202930)
CTNNB1(116-376) [cytosol]
(R-HSA-202950)
CTNNB1 [plasma membrane]
(R-HSA-9038440)
p-S33,S37,T41,S45 CTNNB1 [cytosol]
(R-HSA-8942374)
p-S37,T41,S45, CTNNB1 [cytosol]
(R-HSA-8942369)
p-T41,S45 CTNNB1 [cytosol]
(R-HSA-8942367)
p-S45 CTNNB1 [cytosol]
(R-HSA-8942363)
p-S552-CTNNB1 [cytosol]
(R-HSA-3134933)
p-S552-CTNNB1 [nucleoplasm]
(R-HSA-3134926)
p-Y-CTNNB1 [cytosol]
(R-HSA-8876940)
0.932
12
UniProt:O60716 CTNND1
1
CTNND1 [plasma membrane]
(R-HSA-418996)
0.564
2
UniProt:P14923 JUP
6
JUP [plasma membrane]
(R-HSA-437260)
JUP [specific granule lumen]
(R-HSA-6799534)
JUP [extracellular region]
(R-HSA-6806309)
JUP [ficolin-1-rich granule lumen]
(R-HSA-6801028)
JUP [cornified envelope]
(R-HSA-8847739)
JUP [cytosol]
(R-HSA-201598)
0.564
2
UniProt:Q9UI47 CTNA3
0.527
2
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