Reactome | p-TGOLN2 [endoplasmic reticulum lumen]

p-TGOLN2

Stable Identifier

R-HSA-8956886

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

TGOLN2, Trans-Golgi network integral membrane protein 2, TGON2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43493 TGOLN2

Gene Names

TGOLN2, TGN46, TGN51

Chain

signal peptide:1-21, chain:22-479

Reference Genes

BioGPS Gene:10618 TGOLN2

COSMIC (genes):TGOLN2 TGOLN2

CTD Gene:10618 TGOLN2

dbSNP Gene:10618 TGOLN2

ENSEMBL:ENSG00000152291 TGOLN2

HGNC:15450 TGOLN2

KEGG Gene (Homo sapiens):hsa:10618 TGOLN2

Monarch:10618 TGOLN2

NCBI Gene:10618 TGOLN2

OMIM:603062 TGOLN2

UCSC:O43493 TGOLN2

Reference Transcript

Other Identifiers

0002260162

10618

11489

11716901_s_at

11716902_a_at

11716903_a_at

11716904_s_at

11755687_x_at

12609

12723

16899619

203833_s_at

203834_s_at

212040_3p_at

212040_at

212043_at

2562200

2562201

2562202

2562203

2562204

2562209

2562210

2562211

2562212

2562213

2562214

2562215

2562216

2562217

2562218

2562220

2562221

2562222

31827_s_at

31828_r_at

31829_r_at

38993_r_at

8053388

A_23_P209933

A_24_P413988

CCDS46351

CCDS56126

CCDS56127

ENSG00000152291

ENSP00000366603

ENSP00000381312

ENSP00000386443

ENSP00000391190

ENST00000377386

ENST00000398263

ENST00000409232

ENST00000444342

EntrezGene:10618

g5454115_3p_a_at

GE81643

GE86506

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005654

GO:0005737

GO:0005768

GO:0005783

GO:0005788

GO:0005794

GO:0005802

GO:0005829

GO:0005886

GO:0006464

GO:0006810

GO:0006895

GO:0008150

GO:0016020

GO:0016021

GO:0016192

GO:0030133

GO:0030140

GO:0030665

GO:0031410

GO:0043226

GO:0043687

GO:0044267

GO:0061024

HGNC:15450

Hs.110771.0.S1_3p_x_at

Hs.110771.0.S2_3p_at

Hs.14894.0.S1_3p_a_at

Hs.14894.0.S1_3p_s_at

ILMN_1651735

IPR026084

MIM:603062

NM_001206841

NM_001206844

NM_006464

NP_001193770

NP_001193773

NP_006455

PH_hs_0001402

TC02002035.hg

TGOLN2

TGOLN2-202

TGOLN2-203

TGOLN2-205

TGOLN2-206

uc002soz.4

uc002spb.4

uc002spc.3

uc021vjx.2

UPI0000072C61

UPI0000208801

UPI000020880A

UPI0000EE2512

X94333_at

Participant Of

hasMember

FAM20C products [endoplasmic reticulum lumen]

Other forms of this molecule

TGOLN2 [clathrin-coated vesicle membrane]

TGOLN2 [plasma membrane]

TGOLN2 [Golgi membrane]

TGOLN2 [cytoplasmic vesicle membrane]

TGOLN2 [trans-Golgi network membrane]

TGOLN2 [transport vesicle]

TGOLN2 [endoplasmic reticulum lumen]

Inferred To

Homologues of p-TGOLN2 [endoplasmic reticulum lumen] (Canis familiaris)

phospho-p-TGOLN2 [endoplasmic reticulum lumen] (Bos taurus)

phospho-p-TGOLN2 [endoplasmic reticulum lumen] (Canis familiaris)

phospho-p-TGOLN2 [endoplasmic reticulum lumen] (Danio rerio)

phospho-p-TGOLN2 [endoplasmic reticulum lumen] (Mus musculus)

phospho-p-TGOLN2 [endoplasmic reticulum lumen] (Rattus norvegicus)

phospho-p-TGOLN2 [endoplasmic reticulum lumen] (Sus scrofa)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Cross References

RefSeq

NP_001193769.1, NP_006455.2, NP_001193770.1, NP_001193773.1

GeneCards

O43493

PRO

O43493

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H3P7 ACBD3	1	ACBD3 [Golgi membrane] (R-HSA-8874981)	0.577	5
UniProt:P27986 PIK3R1	15	PIK3R1 K379E [plasma membrane] (R-HSA-8944148) PIK3R1 G376R [plasma membrane] (R-HSA-2399717) PIK3R1 Y463_L466del [plasma membrane] (R-HSA-2399546) PIK3R1 H450_E451del [plasma membrane] (R-HSA-2399545) PIK3R1 R574_T576del [plasma membrane] (R-HSA-2399544) PIK3R1 D560Y [plasma membrane] (R-HSA-2399421) PIK3R1 N564D [plasma membrane] (R-HSA-2399427) PIK3R1 K459del [plasma membrane] (R-HSA-2399554) PIK3R1 N564K [plasma membrane] (R-HSA-2399431) PIK3R1 D560H [plasma membrane] (R-HSA-2399432) PIK3R1 R574I [plasma membrane] (R-HSA-2399536) PIK3R1 R574T [plasma membrane] (R-HSA-2399540) K63polyUb-PIK3R1 [cytosol] (R-HSA-3080572) PIK3R1 [cytosol] (R-HSA-74789) PIK3R1 [plasma membrane] (R-HSA-198365)	0.564	2
UniProt:Q9NZ52 GGA3	3	GGA3 [recycling endosome membrane] (R-HSA-8875655) GGA3 [early endosome membrane] (R-HSA-8854137) GGA3 [endosome membrane] (R-HSA-5692936)	0.491	3
UniProt:Q14739 LBR	1	LBR [nuclear envelope] (R-HSA-194637)	0.462	2
UniProt:Q04721 NOTCH2	18	NOTCH2(1582-1665) [extracellular region] (R-HSA-157652) NICD2 [nucleoplasm] (R-HSA-157942) NOTCH2(1666-1696) [plasma membrane] (R-HSA-157628) NEXT2 [plasma membrane] (R-HSA-157225) NICD2 [cytosol] (R-HSA-157642) Glc,GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] (R-HSA-1911428) Glc,Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] (R-HSA-1911417) Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] (R-HSA-1911505) FRINGE-modified NOTCH2 Extracellular Fragment (NECD2) [plasma membrane] (R-HSA-1911518) FRINGE-modified NOTCH2 extracellular fragment (NECD2) [Golgi membrane] (R-HSA-1911520) Pre-NOTCH2 [endoplasmic reticulum membrane] (R-HSA-157025) 18xFucT-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane] (R-HSA-1467363) 18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane] (R-HSA-1467379) 18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [Golgi membrane] (R-HSA-1472874) NOTCH2(1582-2471) [plasma membrane] (R-HSA-157228) 18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [extracellular region] (R-HSA-1983678) NOTCH2(1582-2471) [Golgi membrane] (R-HSA-157017) 18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [Golgi membrane] (R-HSA-1983676)	0.462	2
UniProt:Q9H2J7 SLC6A15	1	SLC6A15 [plasma membrane] (R-HSA-352060)	0.462	4
UniProt:P35613 BSG	2	BSG [plasma membrane] (R-HSA-197673) BSG [Golgi membrane] (R-HSA-204478)	0.462	2
UniProt:Q07065 CKAP4	7	PALM-C100-CKAP4 [plasma membrane] (R-HSA-5686280) PALM-C100-CKAP4 [lamellar body] (R-HSA-5686285) CKAP4 [azurophil granule membrane] (R-HSA-6799559) CKAP4 [plasma membrane] (R-HSA-5686306) CKAP4 [specific granule membrane] (R-HSA-6799552) p-CKAP4 [endoplasmic reticulum lumen] (R-HSA-8956926) CKAP4 [endoplasmic reticulum lumen] (R-HSA-8956737)	0.462	2
UniProt:Q9NZC7 WWOX	1	WWOX [cytosol] (R-HSA-1253335)	0.462	2
UniProt:Q14677 CLINT1	1	CLINT1 [cytosol] (R-HSA-429811)	0.462	4