Reactome | LAMC1 [endoplasmic reticulum lumen]

LAMC1 [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-8956712

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

Laminin subunit gamma-1, LAMC1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P11047 LAMC1

Gene Names

LAMC1, LAMB2

Chain

signal peptide:1-33, chain:34-1609

Reference Genes

BioGPS Gene:3915 LAMC1

COSMIC (genes):LAMC1 LAMC1

CTD Gene:3915 LAMC1

dbSNP Gene:3915 LAMC1

ENSEMBL:ENSG00000135862 LAMC1

ENSEMBL_homo_sapiens_GENE:ENSG00000135862.6 LAMC1

HGNC:6492 LAMC1

KEGG Gene (Homo sapiens):3915 LAMC1

Monarch:3915 LAMC1

NCBI Gene:3915 LAMC1

OMIM:150290 LAMC1

UCSC:P11047 LAMC1

Reference Transcript

RefSeq:NM_002293.3 LAMC1

Other Identifiers

11716051_at

11716052_s_at

11716053_a_at

11716054_at

16674805

200770_PM_s_at

200770_s_at

200771_PM_at

200771_at

232_at

2371066

2371067

2371092

2371094

2371095

2371100

2371101

2371102

2371103

2371104

2371106

2371107

2371108

2371109

2371110

2371111

2371112

2371115

2371116

2371118

2371120

2371121

2371122

2371123

2371124

2371125

2371127

2371128

2371129

2371130

2371132

2371135

2371136

2371137

2371138

3915

7908041

A_14_P118994

A_23_P201628

GE62877

GO:0005198

GO:0005201

GO:0005576

GO:0005604

GO:0005606

GO:0005615

GO:0005783

GO:0005788

GO:0007155

GO:0007492

GO:0016477

GO:0022617

GO:0023052

GO:0030023

GO:0030154

GO:0030198

GO:0030312

GO:0031012

GO:0031581

GO:0034330

GO:0034446

GO:0035633

GO:0043226

GO:0043259

GO:0043260

GO:0045785

GO:0048856

GO:0048870

GO:0050679

GO:0051149

GO:0062023

GO:0065003

GO:0070062

GO:0098637

GO:0110011

GO:2001046

HMNXSV003004478

M55210_at

PH_hs_0020055

TC01001583.hg

g186916_3p_a_at

g9845497_3p_at

Participates

as a member of

FAM20C substrates [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

p-LAMC1 [endoplasmic reticulum lumen]

LAMC1 [extracellular region]

Inferred To

Megf6 [endoplasmic reticulum lumen] (Mus musculus)

Megf6 [endoplasmic reticulum lumen] (Rattus norvegicus)

MEGF6 [endoplasmic reticulum lumen] (Bos taurus)

MEGF6 [endoplasmic reticulum lumen] (Canis familiaris)

MEGF6 [endoplasmic reticulum lumen] (Sus scrofa)

LAMC1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)

Cross References

RefSeq

NP_002284.3

OpenTargets

ENSG00000135862

HPA

ENSG00000135862-LAMC1

GeneCards

P11047

Ensembl

ENST00000258341, ENSP00000258341, ENSG00000135862

PRO

P11047

Pharos - Targets

P11047

Orphanet

24664

PDB

5XAU, 8DMK, 7CEC

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P01137 TGFB1	7	TGFB1 [extracellular region] (R-HSA-170838) TGFB1(30-278) [extracellular region] (R-HSA-2395367) TGFB1(30-278) [Golgi lumen] (R-HSA-9736812) TGFB1 [Golgi lumen] (R-HSA-177108) TGFB1(30-390) [Golgi lumen] (R-HSA-114705) TGFB1 [plasma membrane] (R-HSA-5146781) TGFB1(30-278) [platelet alpha granule lumen] (R-HSA-65936)	0.527	4
UniProt:Q6UWZ7 FAM175A	1	p-S406-FAM175A [nucleoplasm] (R-HSA-5682575)	0.527	2