Reactome | TGOLN2 [endoplasmic reticulum lumen]

TGOLN2 [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-8956702

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

Trans-Golgi network integral membrane protein 2, TGON2_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43493 TGOLN2

Gene Names

TGOLN2, TGN46, TGN51

Chain

signal peptide:1-21, chain:22-437

Reference Genes

BioGPS Gene:10618 O434935

COSMIC (genes):TGOLN2 TGOLN2

CTD Gene:10618 O434935

dbSNP Gene:10618 O434935

ENSEMBL:ENSG00000152291 TGOLN2

HGNC:15450 O434935

KEGG:hsa:10618 O434935

Monarch:10618 O434935

NCBI Gene:10618 O434935

OMIM:603062 O434935

UCSC:O43493 O434935

Reference Transcript

Participates

as a member of

FAM20C substrates [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

TGOLN2 [clathrin-coated endocytic vesicle membrane]

TGOLN2 [plasma membrane]

TGOLN2 [Golgi membrane]

TGOLN2 [cytoplasmic vesicle membrane]

TGOLN2 [trans-Golgi network membrane]

TGOLN2 [transport vesicle]

p-TGOLN2 [endoplasmic reticulum lumen]

Inferred To

TGOLN2 [endoplasmic reticulum lumen] (Bos taurus)

TGOLN2 [endoplasmic reticulum lumen] (Canis familiaris)

TGOLN2 [endoplasmic reticulum lumen] (Gallus gallus)

TGOLN2 [endoplasmic reticulum lumen] (Sus scrofa)

rgn [endoplasmic reticulum lumen] (Drosophila melanogaster)

Tgoln1 [endoplasmic reticulum lumen] (Mus musculus)

Ttgn1 [endoplasmic reticulum lumen] (Rattus norvegicus)

Cross References

ENSEMBL

ENSG00000292253, ENST00000444342, ENST00000409015, ENSP00000366603, ENSG00000152291, ENST00000377386, ENSP00000518212, ENST00000398263, ENSP00000387035, ENST00000710332, ENSP00000381312, ENSP00000391190

OpenTargets

ENSG00000152291

GeneCards

TGOLN2

HPA

ENSG00000152291-TGOLN2

PRO

O43493

Pharos - Targets

O43493

GlyGen

O43493

PDB

6YAF

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H3P7 ACBD3	1	ACBD3 [Golgi membrane] (R-HSA-8874981)	0.548	5
UniProt:P27986 PIK3R1	16	PIK3R1 [plasma membrane] (R-HSA-198365) PIK3R1 [cytosol] (R-HSA-74789) K63polyUb-PIK3R1 [cytosol] (R-HSA-3080572) PIK3R1 R574T [plasma membrane] (R-HSA-2399540) PIK3R1 R574I [plasma membrane] (R-HSA-2399536) PIK3R1 D560H [plasma membrane] (R-HSA-2399432) PIK3R1 N564K [plasma membrane] (R-HSA-2399431) PIK3R1 K459del [plasma membrane] (R-HSA-2399554) PIK3R1 N564D [plasma membrane] (R-HSA-2399427) PIK3R1 D560Y [plasma membrane] (R-HSA-2399421) PIK3R1 R574_T576del [plasma membrane] (R-HSA-2399544) PIK3R1 H450_E451del [plasma membrane] (R-HSA-2399545) PIK3R1 Y463_L466del [plasma membrane] (R-HSA-2399546) PIK3R1 K379E [plasma membrane] (R-HSA-8944148) PIK3R1 G376R [plasma membrane] (R-HSA-2399717) p-Y-PIK3R1 [cytosol] (R-HSA-9680647)	0.536	2

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