Reactome | MVB12B [endosome membrane]

MVB12B [endosome membrane]

Stable Identifier

R-HSA-8955362

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endosome membrane

Synonyms

Multivesicular body subunit 12B, ESCRT-I complex subunit MVB12B, FAM125B, C9orf28, MB12B_HUMAN

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - Endosomal Sorting Complex Required For Transport (ESCRT) (Homo sapiens)
    - Cargo Recognition And Sorting (Homo sapiens)
      - ESCRT-I [endosome membrane] (Homo sapiens)
        
        MVB12,UBAP1 [endosome membrane] (Homo sapiens)
        
        MVB12 [endosome membrane] (Homo sapiens)
        
        MVB12B [endosome membrane] (Homo sapiens)
      - ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
        
        ESCRT-I [endosome membrane] (Homo sapiens)
        
        MVB12,UBAP1 [endosome membrane] (Homo sapiens)
        
        MVB12 [endosome membrane] (Homo sapiens)
        
        MVB12B [endosome membrane] (Homo sapiens)
    - Cargo Sequestration (Homo sapiens)
      - ESCRT-I [endosome membrane] (Homo sapiens)
        
        MVB12,UBAP1 [endosome membrane] (Homo sapiens)
        
        MVB12 [endosome membrane] (Homo sapiens)
        
        MVB12B [endosome membrane] (Homo sapiens)
      - ESCRT-I/Cargo Complex [endosome membrane] (Homo sapiens)
        
        ESCRT-I [endosome membrane] (Homo sapiens)
        
        MVB12,UBAP1 [endosome membrane] (Homo sapiens)
        
        MVB12 [endosome membrane] (Homo sapiens)
        
        MVB12B [endosome membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9H7P6 MVB12B

Gene Names

MVB12B, C9orf28, FAM125B

Chain

chain:1-319

Reference Genes

BioGPS Gene:89853 MVB12B

COSMIC (genes):MVB12B MVB12B

CTD Gene:89853 MVB12B

dbSNP Gene:89853 MVB12B

ENSEMBL:ENSG00000196814 MVB12B

HGNC:23368 MVB12B

KEGG:hsa:89853 MVB12B

Monarch:89853 MVB12B

NCBI Gene:89853 MVB12B

UCSC:Q9H7P6 MVB12B

Reference Transcript

Other Identifiers

11718825_a_at

11732817_at

11749345_a_at

11752288_a_at

1554065_PM_at

1554065_at

17089147

221687_PM_s_at

221687_s_at

221828_PM_s_at

221828_s_at

3189431

3189432

3189433

3189435

3189438

3189444

3189446

3189447

3189448

3189449

3189450

3189451

3189459

3189462

3189468

3189469

3189470

3189479

3189480

3189481

3189487

3189488

3189489

3189490

3189491

3189492

3189493

3189494

3189495

3189496

3189497

3189498

3189499

3189500

43861_at

45580_s_at

52975_PM_at

52975_at

66350_at

76036_at

8157905

89853

91601_at

A_23_P354591

A_33_P3248439

GE55327

GE857259

GO:0000813

GO:0005515

GO:0005634

GO:0005737

GO:0005768

GO:0005769

GO:0005770

GO:0005829

GO:0005886

GO:0006886

GO:0008289

GO:0010008

GO:0015031

GO:0016020

GO:0016192

GO:0019075

GO:0031902

GO:0031982

GO:0036258

GO:0042058

GO:0043162

GO:0043226

GO:0043328

GO:0046755

GO:0061024

GO:0070062

GO:0090148

HMNXSV003003000

HMNXSV003040001

Hs2.119773.1.S1_3p_s_at

ILMN_1652525

ILMN_1702568

ILMN_2263312

PH_hs_0025714

TC09000654.hg

g12652742_3p_a_at

g12652742_3p_s_at

Participates

as a member of

MVB12 [endosome membrane] (Homo sapiens)

Inferred To

Mvb12b [endosome membrane] (Mus musculus)

Mvb12b [endosome membrane] (Rattus norvegicus)

MVB12B [endosome membrane] (Bos taurus)

MVB12B [endosome membrane] (Canis familiaris)

MVB12B [endosome membrane] (Sus scrofa)

Cross References

RefSeq

NP_001011703.1, NP_258257.1

ENSEMBL

ENST00000361171, ENSP00000485994, ENSG00000196814, ENST00000489637, ENSP00000354772

OpenTargets

ENSG00000196814

GeneCards

MVB12B

HPA

ENSG00000196814-MVB12B

PRO

Q9H7P6

Pharos - Targets

Q9H7P6

GlyGen

Q9H7P6

PDB

3TOW

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