Reactome | DCAF8 [nucleoplasm]

DCAF8 [nucleoplasm]

Stable Identifier

R-HSA-8955192

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DDB1- and CUL4-associated factor 8, DCAF8_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q5TAQ9 DCAF8

Gene Names

DCAF8, H326, WDR42A

Chain

chain:1-597

Reference Genes

BioGPS Gene:50717 Q5TAQ92

COSMIC (genes):DCAF8 DCAF8

CTD Gene:50717 Q5TAQ92

dbSNP Gene:50717 Q5TAQ92

ENSEMBL:ENSG00000132716 DCAF8

HGNC:24891 Q5TAQ92

KEGG:hsa:50717 Q5TAQ92

Monarch:50717 Q5TAQ92

NCBI Gene:50717 Q5TAQ92

OMIM:615820 Q5TAQ92

UCSC:Q5TAQ9 Q5TAQ92

Reference Transcript

RefSeq:NM_015726.3 Q5TAQ92

Participates

as a member of

DCAF protein [nucleoplasm] (Homo sapiens)

Inferred To

iqw1 [nucleoplasm] (Schizosaccharomyces pombe)

Dcaf8 [nucleoplasm] (Mus musculus)

Dcaf8 [nucleoplasm] (Rattus norvegicus)

Dmel\CG8001 [nucleoplasm] (Drosophila melanogaster)

DCAF8 [nucleoplasm] (Bos taurus)

DCAF8 [nucleoplasm] (Canis familiaris)

DCAF8 [nucleoplasm] (Dictyostelium discoideum)

DCAF8 [nucleoplasm] (Sus scrofa)

dcaf8 [nucleoplasm] (Xenopus tropicalis)

Cross References

ENSEMBL

ENST00000368073, ENSP00000357053, ENST00000326837, ENST00000368074, ENSP00000357052, ENST00000475733, ENSP00000318227, ENSP00000476351, ENST00000610139, ENSG00000132716, ENSP00000477464

OpenTargets

ENSG00000132716

GeneCards

DCAF8

HPA

ENSG00000132716-DCAF8

PRO

Q5TAQ9

Pharos - Targets

Q5TAQ9

GlyGen

Q5TAQ9

Orphanet

DCAF8

PDB

3I8E

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q969Q1 TRIM63	1	TRIM63 [cytosol] (R-HSA-976020)	0.537	3
UniProt:Q8WVM0 TFB1M	1	TFB1M [mitochondrial matrix] (R-HSA-1592207)	0.527	2
UniProt:Q709F0 ACAD11	1	ACAD11 [mitochondrial inner membrane] (R-HSA-5695987)	0.527	3
UniProt:P17987 TCP1	1	TCP1 [cytosol] (R-HSA-390448)	0.527	4
UniProt:P52294 KPNA1	2	KPNA1 [cytosol] (R-HSA-180612) KPNA1 [nucleoplasm] (R-HSA-188865)	0.524	2
UniProt:Q99873 PRMT1	2	PRMT1 [cytosol] (R-HSA-9632173) PRMT1 [nucleoplasm] (R-HSA-3215140)	0.508	2
UniProt:O43463 SUV39H1	1	SUV39H1 [nucleoplasm] (R-HSA-427517)	0.508	2