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COMMD6 [nucleoplasm]
Stable Identifier
R-HSA-8955097
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
COMM domain-containing protein 6, COMD6_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Neddylation (Homo sapiens)
AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Homo sapiens)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD6 [nucleoplasm] (Homo sapiens)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD6 [nucleoplasm] (Homo sapiens)
COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD6 [nucleoplasm] (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD6 [nucleoplasm] (Homo sapiens)
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD6 [nucleoplasm] (Homo sapiens)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD6 [nucleoplasm] (Homo sapiens)
NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD6 [nucleoplasm] (Homo sapiens)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD6 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7Z4G1 COMMD6
Gene Names
COMMD6, MSTP076
Chain
chain:1-85
Reference Genes
BioGPS Gene:170622 COMMD6
COSMIC (genes):COMMD6 COMMD6
CTD Gene:170622 COMMD6
dbSNP Gene:170622 COMMD6
ENSEMBL:ENSG00000188243 COMMD6
HGNC:24015 COMMD6
KEGG:hsa:170622 COMMD6
Monarch:170622 COMMD6
NCBI Gene:170622 COMMD6
OMIM:612377 COMMD6
UCSC:Q7Z4G1 COMMD6
Reference Transcript
RefSeq:NM_203497.3 COMMD6
RefSeq:NM_203495.3 COMMD6
Other Identifiers
11733495_a_at
11733496_x_at
11733497_a_at
11753841_x_at
11756875_x_at
16779818
170622
225312_PM_at
225312_at
240030_PM_at
240030_at
3518170
3518171
3518172
3518173
3518175
3518176
3518177
3518178
3518179
3518180
3518181
3518182
3518186
3518187
3518188
3518189
3518190
3518191
3518192
3518196
55316_at
7972044
A_24_P920521
A_32_P114215
GE86005
GO:0005515
GO:0005634
GO:0005737
GO:0006355
GO:0032088
GO:0043226
GO:0051059
HMNXSV003018812
Hs.59590.0.A1_3p_at
Hs.77356.2.A1_3p_at
ILMN_1759997
ILMN_1777378
PH_hs_0017297
Participates
as a candidate of
COMMDs [nucleoplasm] (Homo sapiens)
Other forms of this molecule
COMMD6 [cytosol]
Inferred To
COMMD6 [nucleoplasm]
(Canis familiaris)
COMMD6 [nucleoplasm]
(Gallus gallus)
Commd6 [nucleoplasm]
(Mus musculus)
Commd6 [nucleoplasm]
(Rattus norvegicus)
Homologues of COMMD6 [nucleoplasm]
(Xenopus tropicalis)
LOC101903064 [nucleoplasm]
(Bos taurus)
commd6 [nucleoplasm]
(Dictyostelium discoideum)
commd6 [nucleoplasm]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENST00000355801
,
ENSP00000506987
,
ENST00000682242
,
ENSP00000366841
,
ENSP00000348054
,
ENST00000377615
OpenTargets
ENSG00000188243
HPA
ENSG00000188243-COMMD6
PRO
Q7Z4G1
Pharos - Targets
Q7Z4G1
GlyGen
Q7Z4G1
PDB
8F2R
,
8F2U
,
8P0W
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q14186 TFDP1
1
TFDP1 [nucleoplasm]
(R-HSA-68652)
0.527
3
UniProt:O75461 E2F6
2
E2F6 [nucleoplasm]
(R-HSA-8953089)
p-S12-E2F6 [nucleoplasm]
(R-HSA-9007536)
0.527
3
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