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COMMD5 [nucleoplasm]
Stable Identifier
R-HSA-8955096
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
COMM domain-containing protein 5, COMD5_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Neddylation (Homo sapiens)
AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Homo sapiens)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD5 [nucleoplasm] (Homo sapiens)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD5 [nucleoplasm] (Homo sapiens)
COMMDs displace CAND1 from CRL4 E3 ubiquitin ligase complex (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD5 [nucleoplasm] (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD5 [nucleoplasm] (Homo sapiens)
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD5 [nucleoplasm] (Homo sapiens)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD5 [nucleoplasm] (Homo sapiens)
NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD5 [nucleoplasm] (Homo sapiens)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs:CCDC22 [nucleoplasm] (Homo sapiens)
COMMDs [nucleoplasm] (Homo sapiens)
COMMD5 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9GZQ3 COMMD5
Gene Names
COMMD5, HT002
Chain
initiator methionine:, chain:2-224
Reference Genes
BioGPS Gene:28991 COMMD5
COSMIC (genes):COMMD5 COMMD5
CTD Gene:28991 COMMD5
dbSNP Gene:28991 COMMD5
ENSEMBL:ENSG00000170619 COMMD5
HGNC:17902 COMMD5
KEGG:hsa:28991 COMMD5
Monarch:28991 COMMD5
NCBI Gene:28991 COMMD5
OMIM:608216 COMMD5
UCSC:Q9GZQ3 COMMD5
Reference Transcript
RefSeq:NM_001081004.2 COMMD5
RefSeq:NM_001081003.2 COMMD5
RefSeq:NM_014066.3 COMMD5
RefSeq:NM_001287237.1 COMMD5
Other Identifiers
11758052_s_at
11758704_s_at
17082898
223198_PM_x_at
223198_x_at
223819_PM_x_at
223819_x_at
224387_PM_at
224387_at
28991
3159135
3159136
3159137
3159139
3159140
3159141
3159142
3159143
3159144
3159145
3159146
3159147
3159148
3159149
3159150
44082_at
51601_s_at
8153911
ADDON001033.hg
ADDON001648.hg
A_21_P0014620
A_23_P20255
A_24_P141168
GE61876
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0043226
HMNXSV003023148
ILMN_2235454
ILMN_2300396
PH_hs_0021966
TC08002624.hg
g12803672_3p_s_at
g9964286_3p_at
Participates
as a candidate of
COMMDs [nucleoplasm] (Homo sapiens)
Other forms of this molecule
COMMD5 [cytosol]
Inferred To
LSm-4 [nucleoplasm]
(Drosophila melanogaster)
commd5 [nucleoplasm]
(Danio rerio)
commd5 [nucleoplasm]
(Dictyostelium discoideum)
COMMD5 [nucleoplasm]
(Bos taurus)
COMMD5 [nucleoplasm]
(Canis familiaris)
COMMD5 [nucleoplasm]
(Gallus gallus)
COMMD5 [nucleoplasm]
(Sus scrofa)
Commd5 [nucleoplasm]
(Mus musculus)
Commd5 [nucleoplasm]
(Rattus norvegicus)
Cross References
ENSEMBL
ENSP00000445840
,
ENSP00000394331
,
ENST00000450361
,
ENST00000543949
,
ENSP00000385793
,
ENSP00000304544
,
ENST00000305103
,
ENST00000402718
OpenTargets
ENSG00000170619
HPA
ENSG00000170619-COMMD5
PRO
Q9GZQ3
Pharos - Targets
Q9GZQ3
PDB
8ESD
,
8F2R
,
8P0W
,
8F2U
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