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LRTOMT [plasma membrane]
Stable Identifier
R-HSA-8954996
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
fullName evidence="2"Transmembrane O-methyltransferase ecNumber2.1.1.6/ecNumber, TOMT_HUMAN
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter clearance (Homo sapiens)
Dopamine clearance from the synaptic cleft (Homo sapiens)
Enzymatic degradation of dopamine by COMT (Homo sapiens)
LRTOMT transfers Met to DA, forming 3MT (Homo sapiens)
LRTOMT [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8WZ04 TOMT
Gene Names
LRTOMT, COMT2, TOMT, PP7517
Chain
chain:1-291
Reference Genes
BioGPS Gene:220074 LRTOMT
COSMIC (genes):LRTOMT LRTOMT
CTD Gene:220074 LRTOMT
dbSNP Gene:220074 LRTOMT
ENSEMBL:ENSG00000184154 LRTOMT
HGNC:55527 LRTOMT
KEGG Gene (Homo sapiens):220074 LRTOMT
Monarch:220074 LRTOMT
NCBI Gene:220074 LRTOMT
OMIM:612414 LRTOMT
UCSC:Q8WZ04 LRTOMT
Reference Transcript
RefSeq:NM_001145310.3 LRTOMT
RefSeq:NM_001145309.3 LRTOMT
RefSeq:NM_001145308.4 LRTOMT
Other Identifiers
11735678_a_at
11736624_a_at
11741729_a_at
220074
226717_at
3339312
3339313
3339314
3339315
3339325
3339326
3339327
3339336
3339337
3339338
3339339
3339340
3339341
3339342
3339343
7942315
A_14_P126164
A_23_P98763
A_24_P357914
A_33_P3216651
GO:0003674
GO:0005575
GO:0005622
GO:0005737
GO:0005783
GO:0005886
GO:0006584
GO:0007605
GO:0008150
GO:0008168
GO:0008171
GO:0009056
GO:0016020
GO:0016021
GO:0016206
GO:0016740
GO:0030154
GO:0032259
GO:0032502
GO:0042135
GO:0042417
GO:0042424
GO:0043226
GO:0048856
GO:0050877
GO:0060117
GO:0102084
GO:0102938
HMNXSV003018661
HMNXSV003021780
Inferred To
TOMT [plasma membrane]
(Bos taurus)
Homologues of LRTOMT [plasma membrane]
(Schizosaccharomyces pombe)
Tomt [plasma membrane]
(Mus musculus)
Tomt [plasma membrane]
(Rattus norvegicus)
LRTOMT [plasma membrane]
(Gallus gallus)
LRTOMT [plasma membrane]
(Plasmodium falciparum)
LRTOMT [plasma membrane]
(Schizosaccharomyces pombe)
LRTOMT [plasma membrane]
(Sus scrofa)
LRTOMT [plasma membrane]
(Xenopus tropicalis)
LOC106560171 [plasma membrane]
(Canis familiaris)
tomt [plasma membrane]
(Danio rerio)
Cross References
RefSeq
NP_001138780.1
,
NP_001138781.1
,
NP_001138782.1
OpenTargets
ENSG00000184154
IntEnz
2.1.1.6
HPA
ENSG00000284922-AP000812.4
GeneCards
Q8WZ04
Ensembl
ENSP00000305742
,
ENSG00000284922
,
ENST00000307198
PRO
Q8WZ04
Pharos - Targets
Q8WZ04
Orphanet
17844
HMDB Protein
HMDBP09208
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