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TPST2 [Golgi membrane]
Stable Identifier
R-HSA-8954250
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
Protein-tyrosine sulfotransferase 2 ecNumber2.8.2.20/ecNumber, TPST2_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of hemostasis (Homo sapiens)
Defects of contact activation system (CAS) and kallikrein/kinin system (KKS) (Homo sapiens)
Defective factor VIII causes hemophilia A (Homo sapiens)
Defective F8 sulfation at Y1699 (Homo sapiens)
F8 variant is not sulfonated at Y1699 (Homo sapiens)
TPST1,2 [Golgi membrane] (Homo sapiens)
TPST2 [Golgi membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Cytosolic sulfonation of small molecules (Homo sapiens)
TPST1,2 transfer SO4(2-) from PAPS to PODXL2 (Homo sapiens)
TPST1,2 [Golgi membrane] (Homo sapiens)
TPST2 [Golgi membrane] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
TPST1,2 transfer SO4(2-) from PAPS to FVIII (Homo sapiens)
TPST1,2 [Golgi membrane] (Homo sapiens)
TPST2 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60704 TPST2
Gene Names
TPST2
Chain
chain:1-377
Reference Genes
BioGPS Gene:8459 TPST2
COSMIC (genes):TPST2 TPST2
CTD Gene:8459 TPST2
dbSNP Gene:8459 TPST2
ENSEMBL:ENSG00000128294 TPST2
ENSEMBL_homo_sapiens_GENE:ENSG00000128294.16 TPST2
HGNC:12021 TPST2
KEGG Gene (Homo sapiens):8459 TPST2
Monarch:8459 TPST2
NCBI Gene:8459 TPST2
OMIM:603126 TPST2
UCSC:O60704 TPST2
Reference Transcript
RefSeq:NM_003595.3 TPST2
RefSeq:NM_001008566.1 TPST2
Other Identifiers
11721498_a_at
16933378
204079_PM_at
204079_at
229449_PM_at
229449_at
235761_PM_at
235761_at
35172_at
3955916
3955917
3955918
3955921
3955922
3955924
3955927
3955928
3955929
3955931
3955933
3955939
61348_at
8075106
8459
91825_at
A_23_P132226
A_32_P191941
GE54428
GO:0000139
GO:0003824
GO:0005783
GO:0005794
GO:0006478
GO:0006790
GO:0008476
GO:0016020
GO:0016740
GO:0036211
GO:0042803
GO:0043226
GO:0050427
GO:0055086
GO:0140096
GO:1901135
HMNXSV003026933
HMNXSV003034884
Hs.167167.0.A1_3p_at
Hs.24740.0.A1_3p_at
ILMN_1661488
ILMN_1695432
ILMN_2329679
PH_hs_0010046
PH_hs_0025682
PH_hs_0033427
TC22000610.hg
TC22001279.hg
g4507666_3p_at
p10983
Participates
as a member of
TPST1,2 [Golgi membrane] (Homo sapiens)
Inferred To
tpst2 [Golgi membrane]
(Xenopus tropicalis)
TPST2 [Golgi membrane]
(Bos taurus)
TPST2 [Golgi membrane]
(Canis familiaris)
TPST2 [Golgi membrane]
(Gallus gallus)
TPST2 [Golgi membrane]
(Mus musculus)
TPST2 [Golgi membrane]
(Rattus norvegicus)
TPST2 [Golgi membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001008566.1
,
NP_003586.3
OpenTargets
ENSG00000128294
IntEnz
2.8.2.20
GeneCards
O60704
HPA
ENSG00000128294-TPST2
ZINC target
O60704
Ensembl
ENSP00000339813
,
ENSG00000128294
,
ENSP00000385192
,
ENST00000398110
,
ENSP00000381180
,
ENSP00000400357
,
ENST00000454778
,
ENST00000403880
,
ENST00000338754
PRO
O60704
Pharos - Targets
O60704
Orphanet
24997
PDB
3AP3
,
3AP1
,
3AP2
HMDB Protein
HMDBP00354
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