ERBB4s80:ESR1 binds CXCL12 gene promoter

Stable Identifier
R-HSA-8954207
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
ERBB4s80:ESR1 binds CXCL12 gene promoter
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The complex of ERBB4s80 and activated estrogen receptor ESR1 binds estrogen response elements (EREs) in the promoter of the CXCL12 gene, encoding Stromal cell-derived factor 1 (Zhu et al. 2006).
Literature References
PubMed ID Title Journal Year
16912174 Coregulation of estrogen receptor by ERBB4/HER4 establishes a growth-promoting autocrine signal in breast tumor cells

Zhu, Y, Sullivan, LL, Nair, SS, Williams, CC, Pandey, AK, Marrero, L, Vadlamudi, RK, Jones, FE

Cancer Res 2006
Participants
Input
Output
Participates
as an event of
Authored
Orlic-Milacic, M  (2011-11-04)
Stern, DF  (2019-02-21)
Reviewed
Harris, RC  (2011-11-11)
Zeng, F  (2011-11-11)
Earp HS, 3rd  (2012-02-20)
Misior, AM  (2012-02-20)
Created
Orlic-Milacic, M  (2017-01-05)
Cite Us!