Reactome | PCGF6 [nucleoplasm]

PCGF6 [nucleoplasm]

Stable Identifier

R-HSA-8953572

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Polycomb group RING finger protein 6, MBLR, Mel18 and Bmi1-like RING finger, RNF134, RING finger protein 134

Locations in the PathwayBrowser for interactor UniProt:Q14186 TFDP1

Expand all

External Reference Information

External Reference

UniProt:Q9BYE7 PCGF6

Gene Names

PCGF6, MBLR, RNF134

Chain

chain:1-350

Reference Genes

BioGPS Gene:84108 PCGF6

COSMIC (genes):PCGF6 PCGF6

CTD Gene:84108 PCGF6

dbSNP Gene:84108 PCGF6

ENSEMBL:ENSG00000156374 PCGF6

HGNC:21156 PCGF6

KEGG Gene (Homo sapiens):84108 PCGF6

Monarch:84108 PCGF6

NCBI Gene:84108 PCGF6

OMIM:607816 PCGF6

UCSC:Q9BYE7 PCGF6

Reference Transcript

Other Identifiers

0006400707

11724980_s_at

16718022

224326_s_at

3304719

3304720

3304722

3304724

3304726

3304727

3304728

3304729

3304731

3304732

3304733

3304734

3304735

3304736

3826917

3826919

3826920

3826921

3826922

3826923

3826924

3826925

3826926

3826928

3826932

61670_at

7936083

8027330

84108

A_23_P115703

GE83323

GO:0000122

GO:0000977

GO:0001227

GO:0003674

GO:0003677

GO:0003700

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0006464

GO:0007049

GO:0008150

GO:0009058

GO:0031519

GO:0032991

GO:0034641

GO:0035102

GO:0036353

GO:0043167

GO:0043226

GO:0045892

GO:0045944

GO:0046872

GO:0051276

GO:0060819

GO:0070317

ILMN_1656574

ILMN_1810181

ILMN_2401701

PH_hs_0029782

TC10001628.hg

g13537205_3p_s_at

Participant Of

hasComponent

input

E2F6 forms the PRC1L4 complex

Inferred To

fat1 [nucleoplasm] (Xenopus tropicalis)

Pcgf6 [nucleoplasm] (Mus musculus)

Pcgf6 [nucleoplasm] (Rattus norvegicus)

Ghost homologue of PCGF6 [nucleoplasm] (Canis familiaris)

Ghost homologue of PCGF6 [nucleoplasm] (Drosophila melanogaster)

PCGF6 [nucleoplasm] (Bos taurus)

PCGF6 [nucleoplasm] (Gallus gallus)

PCGF6 [nucleoplasm] (Sus scrofa)

pcgf6 [nucleoplasm] (Danio rerio)

Cross References

RefSeq

NP_001011663.1, NP_115530.2

OpenTargets

ENSG00000156374

GeneCards

Q9BYE7

HPA

ENSG00000156374-PCGF6

Ensembl

ENSG00000156374, ENSP00000338845, ENST00000369847, ENSP00000358862, ENST00000337211

PRO

Q9BYE7

PDB

2DJB

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q99496 RNF2	1	RNF2 [nucleoplasm] (R-HSA-389119)	0.798	6
UniProt:Q9HC52 CBX8	1	CBX8 [nucleoplasm] (R-HSA-389117)	0.723	4
UniProt:O95931 CBX7			0.723	4
UniProt:Q06587 RING1	1	RING1 [nucleoplasm] (R-HSA-389113)	0.659	4
UniProt:P83916 CBX1	1	CBX1 [nucleoplasm] (R-HSA-9653629)	0.643	4
UniProt:Q13185 CBX3	1	CBX3 [nucleoplasm] (R-HSA-427386)	0.643	4
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.643	4
UniProt:Q8N488 RYBP	1	RYBP [nucleoplasm] (R-HSA-8937975)	0.643	4
UniProt:Q8VDS3 CBX7			0.643	3
UniProt:Q14186 TFDP1	1	TFDP1 [nucleoplasm] (R-HSA-68652)	0.643	4
UniProt:Q8WXX7 AUTS2	1	AUTS2 [nucleoplasm] (R-HSA-8937967)	0.643	3
UniProt:Q14188 TFDP2	1	TFDP2 [nucleoplasm] (R-HSA-1362225)	0.527	2
UniProt:Q969R5 L3MBTL2	2	SUMO2-K675,K700-L3MBTL2 [nucleoplasm] (R-HSA-6804480) L3MBTL2 [nucleoplasm] (R-HSA-6804477)	0.527	3
UniProt:Q8IY57 YAF2	1	YAF2 [nucleoplasm] (R-HSA-8937973)	0.527	3
UniProt:Q92769 HDAC2	2	HDAC2 [nucleoplasm] (R-HSA-205135) SUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958)	0.527	2
UniProt:Q13547 HDAC1	2	SUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030) HDAC1 [nucleoplasm] (R-HSA-205021)	0.527	2
UniProt:Q8IWI9 MGA	1	MGA [nucleoplasm] (R-HSA-8953093)	0.527	2
UniProt:O00257 CBX4	2	CBX4 [nucleoplasm] (R-HSA-389118) SUMO1-K494-CBX4 [nucleoplasm] (R-HSA-4551626)	0.527	2
UniProt:O75461 E2F6	2	p-S12-E2F6 [nucleoplasm] (R-HSA-9007536) E2F6 [nucleoplasm] (R-HSA-8953089)	0.527	3
UniProt:P61244 MAX	1	MAX [nucleoplasm] (R-HSA-3006627)	0.527	3
UniProt:O00257-3 CBX4			0.499	2

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