Reactome | DNPH1 [cytosol]

DNPH1 [cytosol]

Stable Identifier

R-HSA-8953358

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

fullName evidence="11"2'-deoxynucleoside 5'-phosphate N-hydrolase 1 ecNumber evidence="11 13 14"3.2.2.-/ecNumber, DNPH1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43598 DNPH1

Gene Names

DNPH1, C6orf108, RCL

Chain

initiator methionine:, chain:2-174

Reference Genes

BioGPS Gene:10591 DNPH1

COSMIC (genes):DNPH1 DNPH1

CTD Gene:10591 DNPH1

dbSNP Gene:10591 DNPH1

ENSEMBL:ENSG00000112667 DNPH1

ENSEMBL_homo_sapiens_GENE:ENSG00000112667.13 DNPH1

HGNC:21218 DNPH1

KEGG Gene (Homo sapiens):10591 DNPH1

Monarch:10591 DNPH1

NCBI Gene:10591 DNPH1

OMIM:618762 DNPH1

UCSC:O43598 DNPH1

Reference Transcript

Other Identifiers

10591

11731099_a_at

17019338

204238_PM_s_at

204238_s_at

2954490

2954491

2954492

2954493

2954494

2954495

2954496

2954499

2954500

39817_PM_s_at

39817_s_at

4919514_3p_s_at

8126524

A_24_P414733

A_33_P3372451

GE79333

GO:0003824

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0005829

GO:0006195

GO:0008152

GO:0009116

GO:0009117

GO:0009159

GO:0016787

GO:0016798

GO:0016799

GO:0030154

GO:0030307

GO:0030855

GO:0042802

GO:0042803

GO:0043174

GO:0043226

GO:0048856

GO:0055086

GO:0070062

GO:0070694

GO:1901135

HMNXSV003013548

ILMN_1722364

ILMN_2380588

PH_hs_0006055

TC06001745.hg

g5454001_3p_at

Inferred To

DNPH1 [cytosol] (Bos taurus)

DNPH1 [cytosol] (Canis familiaris)

DNPH1 [cytosol] (Danio rerio)

DNPH1 [cytosol] (Mus musculus)

DNPH1 [cytosol] (Rattus norvegicus)

DNPH1 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_006434.1, NP_954653.1

OpenTargets

ENSG00000112667

ZINC - Substances

DNPH1_HUMAN

ZINC target

O43598

ZINC - Biogenic

DNPH1_HUMAN

PRO

O43598

PDB

8OS9, 8QHR, 4P5E, 8OSC, 8QHQ

HPA

ENSG00000112667-DNPH1

GeneCards

O43598

Ensembl

ENSP00000377556, ENSP00000230431, ENSG00000112667, ENST00000393987, ENST00000230431

Pharos - Targets

O43598

ZINC - Predictions - Purchasable

DNPH1_HUMAN

HMDB Protein

HMDBP11711

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43598 DNPH1	1	DNPH1 [cytosol] (R-HSA-8953358)	0.742	5
UniProt:Q96D03 DDT4L			0.556	5
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.556	3
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.556	3
UniProt:Q8TAP4-4 LMO3			0.556	3
UniProt:Q15047-2 SETDB1			0.556	3
UniProt:P17252 PRKCA	8	PRKCA [nucleoplasm] (R-HSA-450530) PRKCA [photoreceptor disc membrane] (R-HSA-2648987) PRKCA [cytosol] (R-HSA-58196) pT497,T638,S657-PRKCA [plasma membrane] (R-HSA-4332340) p-T497-PRKCA [cytosol] (R-HSA-5218731) p-T497,T638,S657-PRKCA [cytosol] (R-HSA-4332337) p-T497,T638,S657-PRKCA [nucleoplasm] (R-HSA-5223292) PRKCA [plasma membrane] (R-HSA-156469)	0.556	3
UniProt:P54274 TERF1	1	TERF1 [nucleoplasm] (R-HSA-164618)	0.508	2