Reactome | E2F6:TFDP1 binds to MGA:MAX

E2F6:TFDP1 binds to MGA:MAX

Stable Identifier

R-HSA-8953115

Type

Reaction [binding]

Species

Homo sapiens

Compartment

nucleoplasm

ReviewStatus

5/5

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The E2F6 heterodimer with TFDP1 forms a complex with the heterodimer of MGA and MAX transcription factors. The E2F6:TFDP1:MGA:MAX complex is the core of the E2F6.com-1 complex and is able to bind to E2F, Myc and Brachyury (T box) binding elements in DNA (Ogawa et al. 2002).

Literature References

PubMed ID	Title	Journal	Year
12004135	A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells Livingston, DM, Gaubatz, S, Ishiguro, K, Ogawa, H, Nakatani, Y	Science	2002