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E2F6:TFDP1 binds to MGA:MAX
Stable Identifier
R-HSA-8953115
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
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Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by E2F6 (Homo sapiens)
E2F6:TFDP1 binds to MGA:MAX (Homo sapiens)
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The E2F6 heterodimer with TFDP1 forms a complex with the heterodimer of MGA and MAX transcription factors. The E2F6:TFDP1:MGA:MAX complex is the core of the E2F6.com-1 complex and is able to bind to E2F, Myc and Brachyury (T box) binding elements in DNA (Ogawa et al. 2002).
Literature References
PubMed ID
Title
Journal
Year
12004135
A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells
Livingston, DM
,
Gaubatz, S
,
Ishiguro, K
,
Ogawa, H
,
Nakatani, Y
Science
2002
Participants
Input
E2F6:TFDP1 [nucleoplasm]
(Homo sapiens)
MGA:MAX [nucleoplasm]
(Homo sapiens)
Output
E2F6:TFDP1:MGA:MAX [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Transcriptional Regulation by E2F6 (Homo sapiens)
Orthologous Events
E2F6:TFDP1 binds to MGA:MAX (Bos taurus)
E2F6:TFDP1 binds to MGA:MAX (Canis familiaris)
E2F6:TFDP1 binds to MGA:MAX (Drosophila melanogaster)
E2F6:TFDP1 binds to MGA:MAX (Gallus gallus)
E2F6:TFDP1 binds to MGA:MAX (Mus musculus)
E2F6:TFDP1 binds to MGA:MAX (Rattus norvegicus)
E2F6:TFDP1 binds to MGA:MAX (Sus scrofa)
E2F6:TFDP1 binds to MGA:MAX (Xenopus tropicalis)
Authored
Orlic-Milacic, M (2017-01-05)
Reviewed
Herlihy, A (2017-05-12)
Created
Orlic-Milacic, M (2016-12-22)
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