Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
User Guide
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
Data Model
Computational inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
User Guide
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
Data Model
Computational inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Download
Search ...
Go!
NKIRAS1 [cytosol]
Stable Identifier
R-HSA-8952686
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
NF-kappa-B inhibitor-interacting Ras-like protein 1, KBRS1_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-1 family signaling (Homo sapiens)
Interleukin-1 signaling (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex (Homo sapiens)
NKIRAS [cytosol] (Homo sapiens)
NKIRAS1 [cytosol] (Homo sapiens)
Innate Immune System (Homo sapiens)
Cytosolic sensors of pathogen-associated DNA (Homo sapiens)
ZBP1(DAI) mediated induction of type I IFNs (Homo sapiens)
RIP-mediated NFkB activation via ZBP1 (Homo sapiens)
Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex (Homo sapiens)
NKIRAS [cytosol] (Homo sapiens)
NKIRAS1 [cytosol] (Homo sapiens)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Homo sapiens)
TRAF6 mediated NF-kB activation (Homo sapiens)
Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex (Homo sapiens)
NKIRAS [cytosol] (Homo sapiens)
NKIRAS1 [cytosol] (Homo sapiens)
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 10 (TLR10) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex (Homo sapiens)
NKIRAS [cytosol] (Homo sapiens)
NKIRAS1 [cytosol] (Homo sapiens)
Toll Like Receptor 2 (TLR2) Cascade (Homo sapiens)
Toll Like Receptor TLR1:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex (Homo sapiens)
NKIRAS [cytosol] (Homo sapiens)
NKIRAS1 [cytosol] (Homo sapiens)
Toll Like Receptor TLR6:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex (Homo sapiens)
NKIRAS [cytosol] (Homo sapiens)
NKIRAS1 [cytosol] (Homo sapiens)
Toll Like Receptor 3 (TLR3) Cascade (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex (Homo sapiens)
NKIRAS [cytosol] (Homo sapiens)
NKIRAS1 [cytosol] (Homo sapiens)
Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)
MyD88-independent TLR4 cascade (Homo sapiens)
TRIF(TICAM1)-mediated TLR4 signaling (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex (Homo sapiens)
NKIRAS [cytosol] (Homo sapiens)
NKIRAS1 [cytosol] (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex (Homo sapiens)
NKIRAS [cytosol] (Homo sapiens)
NKIRAS1 [cytosol] (Homo sapiens)
Toll Like Receptor 5 (TLR5) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex (Homo sapiens)
NKIRAS [cytosol] (Homo sapiens)
NKIRAS1 [cytosol] (Homo sapiens)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex (Homo sapiens)
NKIRAS [cytosol] (Homo sapiens)
NKIRAS1 [cytosol] (Homo sapiens)
Toll Like Receptor 9 (TLR9) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Homo sapiens)
Phospho-IKK Complex phosphorylates IkB within the IkB:NFkB Complex (Homo sapiens)
NKIRAS [cytosol] (Homo sapiens)
NKIRAS1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NYS0 NKIRAS1
Gene Names
NKIRAS1, KBRAS1
Chain
chain:1-192
Reference Genes
BioGPS Gene:28512 NKIRAS1
COSMIC (genes):NKIRAS1 NKIRAS1
CTD Gene:28512 NKIRAS1
dbSNP Gene:28512 NKIRAS1
ENSEMBL:ENSG00000197885 NKIRAS1
ENSEMBL_homo_sapiens_GENE:ENSG00000197885 NKIRAS1
HGNC:17899 NKIRAS1
KEGG Gene (Homo sapiens):28512 NKIRAS1
Monarch:28512 NKIRAS1
NCBI Gene:28512 NKIRAS1
OMIM:604496 NKIRAS1
UCSC:Q9NYS0 NKIRAS1
Reference Transcript
RefSeq:XM_005265078.3 NKIRAS1
RefSeq:XM_005265077.4 NKIRAS1
RefSeq:NM_020345.3 NKIRAS1
RefSeq:XM_005265076.3 NKIRAS1
Other Identifiers
0002650398
11723997_a_at
16951548
225930_at
2666104
2666105
2666106
2666107
2666109
2666110
2666111
2666112
2666113
2666121
28512
54816_at
62521
8085788
A_23_P338519
AAF34998
AAH12145
AAH66940
ABC40740
AF229839
AK027749
BAB55341
BC012145
BC066940
CCDS33717
DQ314881
ENSG00000197885
ENSP00000373411
ENSP00000392307
ENSP00000393785
ENSP00000394214
ENSP00000400385
ENSP00000483749
ENST00000388759
ENST00000416026
ENST00000421515
ENST00000425478
ENST00000443659
ENST00000614374
EntrezGene:28512
G5E9P3
GE79636
GO:0000166
GO:0003674
GO:0003924
GO:0005525
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0007165
GO:0007249
GO:0008150
GO:0016020
GO:0043167
HGNC:17899
HPA062521
Hs.173202.0.S2_3p_at
ILMN_1664216
IPR001806
IPR005225
IPR020849
IPR027417
MIM:604496
NKIRAS1
NKIRAS1-201
NKIRAS1-204
NKIRAS1-205
NKIRAS1-206
NKIRAS1-208
NKIRAS1-209
NM_020345
NP_065078
PF00071
PH_hs_0031998
PR00449
SM00173
SM00175
TC03001239.hg
uc003ccj.4
uc003cck.4
uc062hmx.1
uc062hmy.1
uc062hmz.1
uc062hnd.1
UPI000004A03F
XM_005265076
XM_005265077
XM_005265078
XP_005265133
XP_005265134
XP_005265135
XP_024309227
XP_024309228
Participant Of
hasMember
NKIRAS [cytosol]
Inferred To
Homologues of NKIRAS1 [cytosol] (Sus scrofa)
NKIRAS1 [cytosol] (Bos taurus)
NKIRAS1 [cytosol] (Canis familiaris)
NKIRAS1 [cytosol] (Danio rerio)
NKIRAS1 [cytosol] (Mus musculus)
NKIRAS1 [cytosol] (Rattus norvegicus)
NKIRAS1 [cytosol] (Sus scrofa)
NKIRAS1 [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
NP_065078.1
,
XP_005265135.1
,
XP_005265133.1
,
XP_005265134.1
OpenTargets
ENSG00000197885
GeneCards
Q9NYS0
PRO
Q9NYS0
HMDB Protein
HMDBP08473
© 2018
Reactome
