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NEDD8-CRL2 E3 ligase complex [cytosol]
Stable Identifier
R-HSA-8952597
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Neddylation (Homo sapiens)
AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Homo sapiens)
NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
NEDD8-CRL2 E3 ligase complex [cytosol] (Homo sapiens)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Homo sapiens)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
NEDD8-CRL2 E3 ligase complex [cytosol] (Homo sapiens)
Participants
components
CUL2-box protein [cytosol]
(Homo sapiens)
ELOB [cytosol]
(Homo sapiens)
ELOC [cytosol]
(Homo sapiens)
G76-NEDD8-K689-CUL2 [cytosol]
(Homo sapiens)
RBX1 [cytosol]
(Homo sapiens)
Participates
as a component of
NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
Inferred To
NEDD8-CRL2 E3 ligase complex [cytosol]
(Bos taurus)
NEDD8-CRL2 E3 ligase complex [cytosol]
(Caenorhabditis elegans)
NEDD8-CRL2 E3 ligase complex [cytosol]
(Canis familiaris)
NEDD8-CRL2 E3 ligase complex [cytosol]
(Danio rerio)
NEDD8-CRL2 E3 ligase complex [cytosol]
(Dictyostelium discoideum)
NEDD8-CRL2 E3 ligase complex [cytosol]
(Drosophila melanogaster)
NEDD8-CRL2 E3 ligase complex [cytosol]
(Gallus gallus)
NEDD8-CRL2 E3 ligase complex [cytosol]
(Mus musculus)
NEDD8-CRL2 E3 ligase complex [cytosol]
(Rattus norvegicus)
NEDD8-CRL2 E3 ligase complex [cytosol]
(Sus scrofa)
NEDD8-CRL2 E3 ligase complex [cytosol]
(Xenopus tropicalis)
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