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DCUN1D1 [nucleoplasm]
Stable Identifier
R-HSA-8952487
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DCN1-like protein 1, DCNL1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Neddylation (Homo sapiens)
AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Homo sapiens)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Homo sapiens)
DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
DCUN1D1 [nucleoplasm] (Homo sapiens)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
DCUN1D1 [nucleoplasm] (Homo sapiens)
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Homo sapiens)
CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
DCUN1D1 [nucleoplasm] (Homo sapiens)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
DCUN1D1 [nucleoplasm] (Homo sapiens)
NEDD8:AcM-UBE2M binds CRL4 E3 ubiquitin ligase complex (Homo sapiens)
DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
DCUN1D1 [nucleoplasm] (Homo sapiens)
NEDD8-AcM-UBE2M:CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUND1,2,4,5 [nucleoplasm] (Homo sapiens)
DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
DCUN1D1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96GG9 DCUN1D1
Gene Names
DCUN1D1, DCN1, DCUN1L1, RP42, SCCRO
Chain
chain:1-259
Reference Genes
BioGPS Gene:54165 DCUN1D1
COSMIC (genes):DCUN1D1 DCUN1D1
CTD Gene:54165 DCUN1D1
dbSNP Gene:54165 DCUN1D1
ENSEMBL:ENSG00000043093 DCUN1D1
ENSEMBL_homo_sapiens_GENE:ENSG00000043093.15 DCUN1D1
HGNC:18184 DCUN1D1
KEGG Gene (Homo sapiens):54165 DCUN1D1
Monarch:54165 DCUN1D1
NCBI Gene:54165 DCUN1D1
OMIM:605905 DCUN1D1
UCSC:Q96GG9 DCUN1D1
Reference Transcript
RefSeq:NM_020640.3 DCUN1D1
RefSeq:NM_001308101.1 DCUN1D1
Other Identifiers
11726326_a_at
11726327_at
11751625_a_at
11764171_s_at
16961974
218583_PM_s_at
218583_s_at
222678_PM_s_at
222678_s_at
222679_PM_s_at
222679_s_at
237408_PM_at
237408_at
238879_PM_at
238879_at
240781_3p_x_at
240781_PM_x_at
240781_x_at
243396_PM_at
243396_at
2707770
2707771
2707772
2707773
2707774
2707775
2707776
2707777
2707778
2707779
2707780
2707781
2707790
2707791
2707792
2707793
2707808
2918903
3293523
44340_at
47094_r_at
47812_at
54165
56808_at
58439_at
62294_at
62944_at
75613_at
8092321
A_19_P00317933
A_19_P00325903
A_19_P00810971
A_23_P144145
A_24_P166012
A_33_P3290328
GE61678
GE894652
GE897271
GO:0000151
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0031396
GO:0031624
GO:0032182
GO:0036211
GO:0043226
GO:0045116
GO:0097602
GO:2000434
GO:2000436
HMNXSV003012722
HMNXSV003028881
Hs.104613.0.A1_3p_a_at
Hs.104613.0.A2_3p_a_at
Hs.260282.0.A1_3p_at
Hs.260282.1.S1_3p_at
Hs.288442.0.A1_3p_at
Hs.6656.0.A1_3p_at
ILMN_1810719
ILMN_2043865
PH_hs_0029072
PH_hs_0040582
TC03002052.hg
g10190677_3p_a_at
Participates
as a candidate of
DCUN1D1,2,4,5 [nucleoplasm] (Homo sapiens)
Other forms of this molecule
DCUN1D1 [cytosol]
Inferred To
DCUN1D1 [nucleoplasm]
(Bos taurus)
DCUN1D1 [nucleoplasm]
(Canis familiaris)
DCUN1D1 [nucleoplasm]
(Dictyostelium discoideum)
DCUN1D1 [nucleoplasm]
(Gallus gallus)
Dcun1d1 [nucleoplasm]
(Mus musculus)
Dcun1d1 [nucleoplasm]
(Rattus norvegicus)
SCCRO [nucleoplasm]
(Drosophila melanogaster)
dcn-1 [nucleoplasm]
(Caenorhabditis elegans)
dcn1 [nucleoplasm]
(Schizosaccharomyces pombe)
dcun1d1 [nucleoplasm]
(Danio rerio)
dcun1d1 [nucleoplasm]
(Xenopus tropicalis)
Cross References
RefSeq
NP_065691.2
,
NP_001295030.1
OpenTargets
ENSG00000043093
GeneCards
Q96GG9
HPA
ENSG00000043093-DCUN1D1
Ensembl
ENST00000292782
,
ENSG00000043093
,
ENSP00000292782
PRO
Q96GG9
Pharos - Targets
Q96GG9
PDB
5V88
,
6XON
,
4P5O
,
6P5W
,
8OR3
,
6P5V
,
8OR2
,
6XOM
,
6XOQ
,
7KWA
,
5V86
,
5V83
,
6XOL
,
3TDZ
,
6XOP
,
5UFI
,
6BG5
,
6B5Q
,
6BG3
,
6XOO
,
3TDU
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P61081 UBE2M
5
AcM-UBE2M [nucleoplasm]
(R-HSA-8952502)
G76-NEDD8-C111-AcM-UBE2M [nucleoplasm]
(R-HSA-8952508)
UBE2M [cytosol]
(R-HSA-947619)
AcM-UBE2M [cytosol]
(R-HSA-8951627)
G76-NEDD8-C111-AcM-UBE2M [cytosol]
(R-HSA-4419894)
0.744
5
UniProt:Q13616 CUL1
3
G76-NEDD8-K720-CUL1 [cytosol]
(R-HSA-8952519)
CUL1 [nucleoplasm]
(R-HSA-187551)
CUL1 [cytosol]
(R-HSA-174230)
0.669
7
UniProt:Q93034 CUL5
2
CUL5 [cytosol]
(R-HSA-180528)
G76-NEDD8-K724-CUL5 [cytosol]
(R-HSA-8952014)
0.527
6
UniProt:O14641 DVL2
5
pp-DVL2 [cytosol]
(R-HSA-3772398)
p-DVL2 [cytosol]
(R-HSA-201706)
p-DVL2 [clathrin-coated endocytic vesicle]
(R-HSA-5138444)
DVL2 [cytosol]
(R-HSA-201694)
ub-DVL2 [cytosol]
(R-HSA-4652689)
0.488
2
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