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DCUN1D4 [cytosol]
Stable Identifier
R-HSA-8951783
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
DCN1-like protein 4, DCNL4_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Neddylation (Homo sapiens)
26S proteasome degrades HIFalpha (Homo sapiens)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Homo sapiens)
NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
DCUN1Ds [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
DCUN1Ds [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Homo sapiens)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
DCUN1Ds [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
DCUN1Ds [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
AcM-UBE2M transfers NEDD8 to CRL2 E3 ubiquitin ligase complex (Homo sapiens)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex (Homo sapiens)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Homo sapiens)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
DCUN1Ds [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
DCUN1Ds [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
DCUN1Ds [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8-CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8-CRL3 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
DCUN1Ds [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Homo sapiens)
DCUN1Ds [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
DCUN1Ds [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Homo sapiens)
DCUN1Ds [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Homo sapiens)
DCUN1Ds [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8:AcM-UBE2M binds CRL2 E3 ubiquitin ligase complex (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8-AcM-UBE2M:CRL2 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
NEDD8-AcM-UBE2M:CRL3 E3 ubiquitin ligase :DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 (Homo sapiens)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:UBXN7 [cytosol] (Homo sapiens)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds hydroxyprolyl-HIF-alpha (Homo sapiens)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol] (Homo sapiens)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
VHL:EloB,C:NEDD8-CUL2:RBX1 complex ubiquitinylates HIF-alpha (Homo sapiens)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:UBXN7 [cytosol] (Homo sapiens)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5:hydroxyPro-HIF-alpha [cytosol] (Homo sapiens)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
ub-hydroxyPro-HIF-alpha:VHL:EloB:EloC:NEDD8-CUL2:RBX1:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
RBX1:NEDD8-CUL2:EloB,C:VHL:COMMDs:CCDC22:DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1D4 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q92564 DCUN1D4
Gene Names
DCUN1D4, KIAA0276
Chain
chain:1-292
Reference Genes
BioGPS Gene:23142 DCUN1D4
COSMIC (genes):DCUN1D4 DCUN1D4
CTD Gene:23142 DCUN1D4
dbSNP Gene:23142 DCUN1D4
ENSEMBL:ENSG00000109184 DCUN1D4
ENSEMBL_homo_sapiens_GENE:ENSG00000109184.15 DCUN1D4
HGNC:28998 DCUN1D4
KEGG Gene (Homo sapiens):23142 DCUN1D4
Monarch:23142 DCUN1D4
NCBI Gene:23142 DCUN1D4
OMIM:612977 DCUN1D4
UCSC:Q92564 DCUN1D4
Reference Transcript
RefSeq:NM_001287755.1 DCUN1D4
RefSeq:NM_001287757.1 DCUN1D4
RefSeq:NM_015115.3 DCUN1D4
RefSeq:NM_001040402.2 DCUN1D4
Other Identifiers
11720951_a_at
11720952_a_at
11747011_a_at
11749356_a_at
11757927_s_at
16966649
212851_PM_at
212851_at
212853_PM_at
212853_at
212855_PM_at
212855_at
23142
242096_PM_at
242096_at
2726831
2726832
2726833
2726841
2726842
2726851
2726852
2726855
2726856
2726862
2726863
2726868
2726869
2726873
2726881
2726884
2726885
2726886
2726887
2726888
2726889
2726890
2726891
2726892
2726893
2726894
2726895
2726896
35039_at
71337_at
8095009
A_14_P125785
A_14_P137081
A_32_P43812
D87466_at
GE541780
GE62567
GO:0000151
GO:0005515
GO:0005634
GO:0031624
GO:0032182
GO:0036211
GO:0043226
GO:0045116
GO:0097602
GO:2000436
HMNXSV003013579
Hs.213380.0.A1_3p_at
Hs.240112.0.S1_3p_at
Hs.240112.0.S2_3p_at
Hs.240112.0.S3_3p_at
ILMN_1801403
ILMN_2389429
PH_hs_0012332
PH_hs_0023890
Participates
as a candidate of
DCUN1D1,2,4,5 [cytosol] (Homo sapiens)
DCUN1Ds [cytosol] (Homo sapiens)
Other forms of this molecule
DCUN1D4 [nucleoplasm]
Inferred To
SCCRO4 [cytosol]
(Drosophila melanogaster)
dcun1d4 [cytosol]
(Danio rerio)
Dcun1d4 [cytosol]
(Mus musculus)
Dcun1d4 [cytosol]
(Rattus norvegicus)
DCUN1D4 [cytosol]
(Bos taurus)
DCUN1D4 [cytosol]
(Canis familiaris)
DCUN1D4 [cytosol]
(Dictyostelium discoideum)
DCUN1D4 [cytosol]
(Gallus gallus)
DCUN1D4 [cytosol]
(Sus scrofa)
Homologues of DCUN1D4 [cytosol]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_001274684.1
,
NP_001274686.1
,
NP_001035492.1
,
NP_055930.2
OpenTargets
ENSG00000109184
HPA
ENSG00000109184-DCUN1D4
GeneCards
Q92564
Ensembl
ENST00000451288
,
ENST00000381441
,
ENSP00000370850
,
ENSP00000389900
,
ENSG00000109184
,
ENST00000334635
,
ENSP00000334625
PRO
Q92564
Pharos - Targets
Q92564
PDB
5V89
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