LTF:2xCO3(2-) dissociates from Carbocymycobactin:Fe3+

Stable Identifier
R-HSA-8951552
Type
Reaction [dissociation]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
phagocytic vesicle lumen
ReviewStatus
5/5
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LTF:2xCO3(2-) dissociates from Carbocymycobactin:Fe3+
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Since bacterial siderophores bind iron with much greater affinity, they can scavenge iron ions from loaded lactoferrin (Madigan et al. 2012).
Literature References
PubMed ID Title Journal Year
22232695 Lipidomic discovery of deoxysiderophores reveals a revised mycobactin biosynthesis pathway in Mycobacterium tuberculosis

Layre, E, McConnell, MJ, Rodriguez, GM, Barry CE, 3rd, Debono, CA, Moody, DB, Cheng, TY, Young, DC, Murry, JP, Matsunaga, I, Rubin, EJ, Wei, JR, Madigan, CA

Proc Natl Acad Sci U S A 2012
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2011-01-10)
Reviewed
Warner, D  (2012-04-30)
Created
Jassal, B  (2016-12-08)
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