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Y963-STAT4 dimer [nucleoplasm]
Stable Identifier
R-HSA-8950759
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
2xp-Y693-STAT4
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-12 family signaling (Homo sapiens)
Interleukin-12 signaling (Homo sapiens)
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation (Homo sapiens)
Expression U2 small nuclear ribonucleoprotein A' (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of ADP-ribosylation factor 1 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Aryl Hydrocarbon receptor-interacting protein (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of BolA-like protein 2 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Carbonic anhydrase 1 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Cofilin-1 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Glutathione S-transferase omega-1 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Heterogeneous nuclear ribonucleoprotein D-like (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Heterogeneous nuclear ribonucleoproteins A2/B1 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of IFNG gene (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Interleukin-10 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Lamin-B1 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Macrophage migration inhibitory factor (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Moesin (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of PAK2 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Peptidyl-prolyl cis-trans isomerase A (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Phosphatidylinositol transfer protein alpha isoform (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Plasminogen activator inhibitor 2 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Programmed cell death protein 4 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Proteasome activator complex subunit 2 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Ras-related protein Ral-A (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Ras-related protein Rap-1b (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of S-methyl-5'-thioadenosine phosphorylase (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of SOD1 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of Stress-70 protein, mitochondrial (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of TCP1 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of annexin A2 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of calponin-2 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of capping actin protein of muscle Z-line alpha subunit 1 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of cell division cycle 42 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of glutathione S-transferase alpha 2 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of heterogeneous nuclear ribonucleoprotein F (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of lymphocyte cytosolic protein 1 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of ribosomal protein lateral stalk subunit P0 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of superoxide dismutase 2 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Expression of transaldolase 1 (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Y693-STAT4 dimer translocates to the nucleus (Homo sapiens)
Y963-STAT4 dimer [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
9890938
Identification of a STAT4 binding site in the interleukin-12 receptor required for signaling
Hoey, T
,
McKinney, J
,
Salvekar, A
,
Naeger, LK
J. Biol. Chem.
1999
Participants
components
x 2
p-Y693-STAT4 [nucleoplasm]
(Homo sapiens)
Participates
as an output of
Y693-STAT4 dimer translocates to the nucleus (Homo sapiens)
This entity regulates
Negatively
Expression of Stress-70 protein, mitochondrial
(Homo sapiens)
Expression of Moesin
(Homo sapiens)
Expression of superoxide dismutase 2
(Homo sapiens)
Expression of heterogeneous nuclear ribonucleoprotein F
(Homo sapiens)
Expression of Phosphatidylinositol transfer protein alpha isoform
(Homo sapiens)
Expression of Lamin-B1
(Homo sapiens)
Expression of lymphocyte cytosolic protein 1
(Homo sapiens)
Expression of ADP-ribosylation factor 1
(Homo sapiens)
Expression of Glutathione S-transferase omega-1
(Homo sapiens)
Expression of transaldolase 1
(Homo sapiens)
Expression U2 small nuclear ribonucleoprotein A'
(Homo sapiens)
Expression of annexin A2
(Homo sapiens)
Expression of Ras-related protein Rap-1b
(Homo sapiens)
Expression of Heterogeneous nuclear ribonucleoproteins A2/B1
(Homo sapiens)
Expression of capping actin protein of muscle Z-line alpha subunit 1
(Homo sapiens)
Expression of cell division cycle 42
(Homo sapiens)
Expression of PAK2
(Homo sapiens)
Expression of Plasminogen activator inhibitor 2
(Homo sapiens)
Expression of ribosomal protein lateral stalk subunit P0
(Homo sapiens)
Positively
Expression of Cofilin-1
(Homo sapiens)
Expression of Proteasome activator complex subunit 2
(Homo sapiens)
Expression of BolA-like protein 2
(Homo sapiens)
Expression of Macrophage migration inhibitory factor
(Homo sapiens)
Expression of Programmed cell death protein 4
(Homo sapiens)
Expression of Ras-related protein Ral-A
(Homo sapiens)
Expression of Heterogeneous nuclear ribonucleoprotein D-like
(Homo sapiens)
Expression of S-methyl-5'-thioadenosine phosphorylase
(Homo sapiens)
Expression of IFNG gene
(Homo sapiens)
Expression of Carbonic anhydrase 1
(Homo sapiens)
Expression of Interleukin-10
(Homo sapiens)
Expression of calponin-2
(Homo sapiens)
Expression of Peptidyl-prolyl cis-trans isomerase A
(Homo sapiens)
Expression of Aryl Hydrocarbon receptor-interacting protein
(Homo sapiens)
Expression of glutathione S-transferase alpha 2
(Homo sapiens)
Expression of TCP1
(Homo sapiens)
Expression of SOD1
(Homo sapiens)
Inferred To
Y963-STAT4 dimer [nucleoplasm]
(Bos taurus)
Y963-STAT4 dimer [nucleoplasm]
(Caenorhabditis elegans)
Y963-STAT4 dimer [nucleoplasm]
(Canis familiaris)
Y963-STAT4 dimer [nucleoplasm]
(Dictyostelium discoideum)
Y963-STAT4 dimer [nucleoplasm]
(Drosophila melanogaster)
Y963-STAT4 dimer [nucleoplasm]
(Gallus gallus)
Y963-STAT4 dimer [nucleoplasm]
(Mus musculus)
Y963-STAT4 dimer [nucleoplasm]
(Sus scrofa)
Y963-STAT4 dimer [nucleoplasm]
(Xenopus tropicalis)
Cross References
ComplexPortal
CPX-6050
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