Homodimeric protein of Interleukin-12 beta subunit (IL12B or IL12p40) can be secreted to exert its inhibitory function over Interleukin-12 heterodimer interleukin-12 receptor interaction. The secretion has been shown experimentally in COS cells and by mean of ELISA assays (PMID: 7527811).
Ling, P, Gately, MK, Gubler, U, Stern, AS, Lin, P, Hollfelder, K, Su, C, Pan, YC, Hakimi, J
© 2021 Reactome
