IL12A:IL12B translocates from ER lumen to Golgi

Stable Identifier
R-HSA-8950575
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen, Golgi lumen
Synonyms
Interleukin-12 traslocate to the Golgi compartment
ReviewStatus
5/5
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IL12A:IL12B translocates from ER lumen to Golgi
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Inferred from mouse :
Interleukin-12, (IL12) formed from Interleukin-12 subunit alpha (IL12A) and Interleukin-12 subunit beta (IL12B), has been localized intracellularly in late endocytic vesicles expresing the marker protein termed Vesicle-associated membrane protein 7 (VAMP7) (Chiaruttini et al. 2016).

This reaction is a black box event because we do not fully understand the mechanism of translocation.

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Inferred From
Il12a:Il12b translocates from ER lumen to Golgi (Mus musculus)
Authored
Duenas, C  (2016-12-02)
Reviewed
van de Vosse, E  (2017-05-12)
Created
Duenas, C  (2016-12-02)
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