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Expression of lymphocyte cytosolic protein 1
Stable Identifier
R-HSA-8950426
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cell junction
,
nucleoplasm
Synonyms
Expression of LCP1
ReviewStatus
5/5
Locations in the PathwayBrowser
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Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-12 family signaling (Homo sapiens)
Interleukin-12 signaling (Homo sapiens)
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation (Homo sapiens)
Expression of lymphocyte cytosolic protein 1 (Homo sapiens)
General
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Experiments using human cord blood CD4(+) T cells show 22 protein spots and 20 protein spots, upregulated and downregulated proteins respectively, following Interleukin-12 stimulation (Rosengren et.al, 2005). Among the down-regulated proteins is :Plastin-2(LCP1).
Literature References
PubMed ID
Title
Journal
Year
16038020
Proteome profiling of interleukin-12 treated human T helper cells
Nyman, TA
,
Lahesmaa, R
,
Rosengren, AT
Proteomics
2005
Participants
Input
LCP1 gene [nucleoplasm]
(Homo sapiens)
Output
LCP1 [cell junction]
(Homo sapiens)
Participates
as an event of
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation (Homo sapiens)
This event is regulated
Negatively by
Regulator
Y963-STAT4 dimer [nucleoplasm]
(Homo sapiens)
Authored
Duenas, C (2016-12-02)
Reviewed
van de Vosse, E (2017-05-12)
Created
Duenas, C (2016-12-02)
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