IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2

Stable Identifier
R-HSA-8950186
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
23673666 Identification of canonical tyrosine-dependent and non-canonical tyrosine-independent STAT3 activation sites in the intracellular domain of the interleukin 23 receptor

Floss, DM, Mrotzek, S, Klöcker, T, Schröder, J, Grötzinger, J, Rose-John, S, Scheller, J

J. Biol. Chem. 2013
27193299 Defining the functional binding sites of interleukin 12 receptor ?1 and interleukin 23 receptor to Janus kinases

Floss, DM, Klöcker, T, Schröder, J, Lamertz, L, Mrotzek, S, Strobl, B, Hermanns, H, Scheller, J

Mol. Biol. Cell 2016
Participants
components
Participant Of
input
output
hasComponent
Inferred From
Il12b:Il23a:Il12rb1:p-Y-Tyk2:p-Y542-Il23r,p-Y626-Il23r,p-Il23r:p-Jak2 [plasma membrane] (Mus musculus)
Inferred To
IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2 [plasma membrane] (Bos taurus)
IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2 [plasma membrane] (Canis familiaris)
IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2 [plasma membrane] (Danio rerio)
IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2 [plasma membrane] (Gallus gallus)
IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2 [plasma membrane] (Mus musculus)
IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2 [plasma membrane] (Rattus norvegicus)
IL23A:IL12B:IL12RB1:p-TYK2:p-Y-IL23R:p-JAK2 [plasma membrane] (Sus scrofa)