IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane]

Stable Identifier
R-HSA-8950116
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
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General
Transfected COS cells express the Interleukin-12 receptor subunit both as monomers, and the dimerization or oligomerization of both receprots does not depend on Interleukin-12 binding. Anyway if Interleukin-12 is prebound to these cells, the resulting banding pattern does not change (PMID:7911493)
Literature References
PubMed ID Title Journal Year
7911493 Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130

Chua, AO, Chizzonite, R, Desai, BB, Truitt, TP, Nunes, P, Minetti, LJ, Warrier, RR, Presky, DH, Levine, JF, Gately, MK

J. Immunol. 1994
Participants
components
Participates
as an input of
as an output of
Inferred To
IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane] (Bos taurus)
IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane] (Canis familiaris)
IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane] (Gallus gallus)
IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane] (Mus musculus)
IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane] (Rattus norvegicus)
IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane] (Sus scrofa)
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