IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 [plasma membrane]

Stable Identifier
R-HSA-8950116
Type
Complex
Species
Homo sapiens
Compartment
General

Transfected COS cells express the Interleukin-12 receptor subunit both as monomers, and the dimerization or oligomerization of both receprots does not depend on Interleukin-12 binding. Anyway if Interleukin-12 is prebound to these cells, the resulting banding pattern does not change (PMID:7911493)

Literature References
PubMed ID Title Journal Year
7911493 Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130

Chua, AO, Chizzonite, R, Desai, BB, Truitt, TP, Nunes, P, Minetti, LJ, Warrier, RR, Presky, DH, Levine, JF, Gately, MK

J. Immunol. 1994
Participants
Participant Of
Inferred To