Reactome | TMEM11 [mitochondrial inner membrane]

TMEM11 [mitochondrial inner membrane]

Stable Identifier

R-HSA-8949578

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Transmembrane protein 11, mitochondrial, TMM11_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q92633 LPAR1

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External Reference Information

External Reference

UniProt:P17152 TMEM11

Gene Names

TMEM11, C17orf35, PM1

Chain

chain:1-192

Reference Genes

BioGPS Gene:8834 TMEM11

COSMIC (genes):TMEM11 TMEM11

CTD Gene:8834 TMEM11

dbSNP Gene:8834 TMEM11

ENSEMBL:ENSG00000178307 TMEM11

ENSEMBL_homo_sapiens_GENE:ENSG00000178307.10 TMEM11

HGNC:16823 TMEM11

KEGG Gene (Homo sapiens):8834 TMEM11

Monarch:8834 TMEM11

NCBI Gene:8834 TMEM11

OMIM:618817 TMEM11

UCSC:P17152 TMEM11

Reference Transcript

RefSeq:NM_003876.2 TMEM11

Other Identifiers

11719865_s_at

203437_PM_at

203437_at

31860_at

3749768

3749769

3749770

3749781

8834

A_23_P107036

GE59763

GO:0003674

GO:0005515

GO:0005739

GO:0005743

GO:0005886

GO:0007005

GO:0007007

GO:0016020

GO:0043226

GO:0061024

HMNXSV003016296

ILMN_2175265

PH_hs_0001419

X51804_at

g4505900_3p_at

Participates

as a component of

MIB [mitochondrial inner membrane] (Homo sapiens)

as an input of

Formation of MIB complex containing the MICOS complex causes curvature of mitochondrial inner membrane (Homo sapiens)

Cross References

RefSeq

NP_003867.1

OpenTargets

ENSG00000178307

HPA

ENSG00000178307-TMEM11

GeneCards

P17152

Ensembl

ENSP00000319992, ENST00000317635, ENSG00000178307

PRO

P17152

Pharos - Targets

P17152

Interactors (53)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12983 BNIP3			0.919	12
UniProt:O60238 BNIP3L	1	BNIP3L [mitochondrial outer membrane] (R-HSA-6798001)	0.841	9
UniProt:Q8N6L0 KASH5			0.696	5
UniProt:Q969F0 FATE1			0.666	4
UniProt:O43557 TNFSF14	1	TNFSF14 [plasma membrane] (R-HSA-5667149)	0.666	4
UniProt:Q96BA8 CREB3L1	7	CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.666	6
UniProt:Q9NTQ9 GJB4	1	GJB4 [endoplasmic reticulum membrane] (R-HSA-190624)	0.556	3
UniProt:P11912 CD79A	2	p-Y188,Y199-CD79A [plasma membrane] (R-HSA-983539) CD79A [plasma membrane] (R-HSA-197154)	0.556	3
UniProt:Q96KR6 F210B			0.556	3
UniProt:P15941-11 MUC1			0.556	3
UniProt:Q8TBP5 F174A			0.556	3
UniProt:P49447 CY561			0.556	3
UniProt:Q6PEY1 TMM88			0.556	3
UniProt:P32243-2 OTX2			0.556	3
UniProt:Q96EC8 YIPF6	2	YIPF6 [Golgi membrane] (R-HSA-434346) YIPF6 [cytoplasmic vesicle membrane] (R-HSA-434199)	0.556	3
UniProt:Q16585 SGCB			0.556	3
UniProt:Q96L08 SUSD3			0.556	3
UniProt:O95214 LERL1			0.556	3
UniProt:Q5JX71 F209A			0.556	3
UniProt:Q9GZR5 ELOVL4	1	ELOVL4 [endoplasmic reticulum membrane] (R-HSA-548705)	0.556	3
UniProt:Q86VR2 RETR3			0.556	3
UniProt:Q15800 MSMO1	1	MSMO1 [endoplasmic reticulum membrane] (R-HSA-194648)	0.556	3
UniProt:Q8N6K0 TEX29			0.556	3
UniProt:Q7Z5B4-5 RIC3			0.556	3
UniProt:Q8WUJ1 NEUFC			0.556	3
UniProt:Q6IN84 MRM1	1	MRM1 [mitochondrial matrix] (R-HSA-6793088)	0.556	3
UniProt:O60930 RNH1			0.556	3
UniProt:Q6NSX1 CCD70			0.556	3
UniProt:Q13113 PDZ1I			0.556	3
UniProt:Q9NUH8 TM14B			0.556	3
UniProt:O15552 FFAR2	1	FFAR2 [plasma membrane] (R-HSA-443944)	0.556	3
UniProt:Q3SXY8 ARL13B	8	PolyUb-Misfolded ARL13B [lysosomal lumen] (R-HSA-9660004) PolyUb-Misfolded ARL13B [cytosol] (R-HSA-9641129) Ub-Misfolded ARL13B [cytosol] (R-HSA-9641119) Misfolded ARL13B [cytosol] (R-HSA-9640110) Misfolded ARL13B [cilium] (R-HSA-9640116) ARL13B [cilium] (R-HSA-5618181) PolyUb-Misfolded ARL13B [late endosome lumen] (R-HSA-9659986) ARL13B [plasma membrane] (R-HSA-9716787)	0.556	3
UniProt:Q15125 EBP	1	EBP [endoplasmic reticulum membrane] (R-HSA-195697)	0.556	3
UniProt:Q13323 BIK			0.556	3
UniProt:O15393-2 TMPRSS2			0.556	3
IntAct:EBI-22344578 CCSB ORF ID			0.556	3
UniProt:Q8IWU4 SLC30A8	2	SLC30A8 [Golgi membrane] (R-HSA-9817561) SLC30A8 [secretory granule membrane] (R-HSA-437106)	0.556	3
UniProt:Q96Q45-2 TMEM237			0.556	3
UniProt:Q9H2K0 MTIF3	1	MTIF3 [mitochondrial matrix] (R-HSA-5368284)	0.556	3
UniProt:Q5T7V8 GORAB			0.556	3
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.556	3
UniProt:Q9BVX2 T106C			0.556	3
UniProt:O00623 PEX12	2	PEX12 [cytosol] (R-HSA-9603782) PEX12 [peroxisomal membrane] (R-HSA-8953911)	0.556	3
UniProt:O95471 CLDN7	2	CLDN7 [cell junction] (R-HSA-421241) CLDN7 [plasma membrane] (R-HSA-420004)	0.556	3
UniProt:Q3KNW5 SLC10A6	1	SLC10A6 [plasma membrane] (R-HSA-433091)	0.556	3
UniProt:Q6UW68 TM205			0.556	3
UniProt:Q9H8X2 IPPK	2	IPPK [cytosol] (R-HSA-1604598) IPPK [nucleoplasm] (R-HSA-2023949)	0.527	2
UniProt:Q86VZ1 P2RY8			0.527	3
UniProt:P50895 BCAM			0.527	2
UniProt:Q92633 LPAR1	1	LPAR1 [plasma membrane] (R-HSA-419354)	0.527	2
UniProt:P04201 MAS			0.527	2
UniProt:P34741 SDC2	20	SDC2 [plasma membrane] (R-HSA-2090052) p-Y179,Y191-SDC2 [plasma membrane] (R-HSA-4093306) SDC2 [lysosomal lumen] (R-HSA-2090083) HS(6)-SDC2 [lysosomal lumen] (R-HSA-2090064) HS(1)-SDC2 [Golgi lumen] (R-HSA-2076607) HS(2)-SDC2 [Golgi lumen] (R-HSA-2076603) HS(3)-SDC2 [Golgi lumen] (R-HSA-2076443) HS(4)-SDC2 [Golgi lumen] (R-HSA-2076356) HS(6)-SDC2 [Golgi lumen] (R-HSA-2076588) HS(5)-SDC2 [Golgi lumen] (R-HSA-2076320) Heparan-SDC2 [Golgi lumen] (R-HSA-2076608) Heparan(1)-SDC2 [Golgi lumen] (R-HSA-2076536) Heparan(2)-SDC2 [Golgi lumen] (R-HSA-2076397) Heparan(4)-SDC2 [Golgi lumen] (R-HSA-2076576) Heparan(3)-SDC2 [Golgi lumen] (R-HSA-2076361) SDC2 [Golgi lumen] (R-HSA-2054101) HS(4)-SDC2 [plasma membrane] (R-HSA-2076683) HS(6)-SDC2 [plasma membrane] (R-HSA-2076661) HS(2)-SDC2 [plasma membrane] (R-HSA-2076644) HS(1)-SDC2 [plasma membrane] (R-HSA-2076643)	0.527	2
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.527	2

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