Reactome | CHCHD6 (MIC25) [mitochondrial inner membrane]

CHCHD6 (MIC25) [mitochondrial inner membrane]

Stable Identifier

R-HSA-8949568

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

CHCHD6, MICOS complex subunit MIC25, MIC25_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9BRQ6 CHCHD6

Gene Names

CHCHD6, CHCM1, MIC25

Chain

initiator methionine:, chain:2-235

Reference Genes

BioGPS Gene:84303 CHCHD6

COSMIC (genes):CHCHD6 CHCHD6

CTD Gene:84303 CHCHD6

dbSNP Gene:84303 CHCHD6

ENSEMBL:ENSG00000159685 CHCHD6

HGNC:28184 CHCHD6

KEGG:hsa:84303 CHCHD6

Monarch:84303 CHCHD6

NCBI Gene:84303 CHCHD6

OMIM:615634 CHCHD6

UCSC:Q9BRQ6 CHCHD6

Reference Transcript

Other Identifiers

11721850_a_at

11721851_x_at

16945034

224462_PM_s_at

224462_s_at

2640508

2640509

2640512

2640513

2640515

2640530

2640541

2640543

2640551

2640554

2640555

2640556

2640557

2640558

2640560

2640564

2640565

2640566

2640567

2640569

2640570

2640571

2640572

8082305

84303

91662_at

A_14_P125652

A_23_P91870

A_33_P3235975

GE86952

GO:0001401

GO:0005515

GO:0005739

GO:0005743

GO:0005829

GO:0006974

GO:0007005

GO:0007007

GO:0016020

GO:0042407

GO:0043226

GO:0044284

GO:0061024

GO:0061617

GO:0140275

HMNXSV003022972

ILMN_1785161

PH_hs_0004788

PH_hs_0034449

g13543969_3p_s_at

Participates

as a component of

MICOS [mitochondrial inner membrane] (Homo sapiens)

as an input of

Formation of MIB complex containing the MICOS complex causes curvature of mitochondrial inner membrane (Homo sapiens)

Cross References

ENSEMBL

ENSP00000290913, ENSG00000159685, ENST00000290913

OpenTargets

ENSG00000159685

GeneCards

CHCHD6

HPA

ENSG00000159685-CHCHD6

PRO

Q9BRQ6

Pharos - Targets

Q9BRQ6

GlyGen

Q9BRQ6

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75431 MTX2	1	MTX2 [mitochondrial outer membrane] (R-HSA-1252142)	0.643	4
UniProt:Q9NX63 CHCHD3	3	CHCHD3 [mitochondrial intermembrane space] (R-HSA-8874907) 4xHC-CHCHD3 [mitochondrial intermembrane space] (R-HSA-8874910) CHCHD3 (MIC19) [mitochondrial inner membrane] (R-HSA-8949583)	0.564	2
UniProt:Q9Y512 SAMM50	1	SAMM50 [mitochondrial outer membrane] (R-HSA-1252178)	0.556	3
UniProt:Q86VW1 SLC22A16	1	SLC22A16 [plasma membrane] (R-HSA-561104)	0.527	2
UniProt:Q6UXV4 APOOL	3	APOOL (MIC27) [mitochondrial inner membrane] (R-HSA-8949612) APOOL [extracellular region] (R-HSA-8862979) APOOL [platelet alpha granule lumen] (R-HSA-8863003)	0.527	4
UniProt:Q9NY25 CLEC5A	3	CLEC5A [specific granule membrane] (R-HSA-6799520) CLEC5A [plasma membrane] (R-HSA-210028) CLEC5A [tertiary granule membrane] (R-HSA-6801019)	0.527	2
UniProt:Q8WYQ3 CHCHD10	2	4xHC-CHCHD10 [mitochondrial intermembrane space] (R-HSA-8874883) CHCHD10 [mitochondrial intermembrane space] (R-HSA-8874860)	0.471	2

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