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CAR translocates from the cytosol to the mitochondrial intermembrane space
Stable Identifier
R-HSA-8949399
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol
,
mitochondrial intermembrane space
ReviewStatus
5/5
Locations in the PathwayBrowser
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Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Carnitine metabolism (Homo sapiens)
CAR translocates from the cytosol to the mitochondrial intermembrane space (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
CAR (carnitine) diffuses across the mitochondrial outer membrane from the cytosol to the mitochondrial intermembrane space, presumably via porin channels in the outer membrane (Bay & Court 2002).
Literature References
PubMed ID
Title
Journal
Year
12440696
Origami in the outer membrane: the transmembrane arrangement of mitochondrial porins
Bay, DC
,
Court, DA
Biochem. Cell Biol.
2002
Participants
Input
CAR [cytosol]
Output
CAR [mitochondrial intermembrane space]
Participates
as an event of
Carnitine metabolism (Homo sapiens)
Event Information
Go Biological Process
carnitine transport (0015879)
Authored
D'Eustachio, P (2016-11-23)
Reviewed
Jassal, B (2016-12-23)
Created
D'Eustachio, P (2016-11-23)
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