miR-106a,(miR106b) microRNA binds CNOT6L mRNA

Stable Identifier
R-HSA-8948651
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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MicroRNA miR-106a (possibly also miR-106b) binds the CNOT5L mRNA. CNOT6L mRNA acts as a competing endogenous RNA (ceRNA) for PTEN, preventing binding of miR-106a microRNA to PTEN mRNA and PTEN downregulation (Tay et al. 2011).

Literature References
PubMed ID Title Journal Year
22000013 Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs

Tay, Y, Kats, L, Salmena, L, Weiss, D, Tan, SM, Ala, U, Karreth, F, Poliseno, L, Provero, P, Di Cunto, F, Lieberman, J, Rigoutsos, I, Pandolfi, PP

Cell 2011
Participants
Participant Of
Authored
Created