miR-106 microRNAs bind VAPA mRNA

Stable Identifier
R-HSA-8948641
Type
Reaction [binding]
Species
Homo sapiens
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MicroRNAs miR-106a and miR-106b bind the VAPA mRNA. VAPA mRNA acts as a competing endogenous RNA (ceRNA) for PTEN, preventing binding of miR-106 microRNAs to PTEN mRNA and PTEN downregulation (Tay et al. 2011).

Literature References
PubMed ID Title Journal Year
22000013 Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs

Tay, Y, Kats, L, Salmena, L, Weiss, D, Tan, SM, Ala, U, Karreth, F, Poliseno, L, Provero, P, Di Cunto, F, Lieberman, J, Rigoutsos, I, Pandolfi, PP

Cell 2011
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