miR-20 microRNAs bind CNOT6L mRNA

Stable Identifier
R-HSA-8948623
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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miR-20 microRNAs bind CNOT6L mRNA
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MicroRNAs miR-20a and miR-20b bind the CNOT6L mRNA. CNOT6L mRNA acts as a competing endogenous RNA (ceRNA) for PTEN, preventing binding of miR-20 microRNAs to PTEN mRNA and PTEN downregulation (Tay et al. 2011).
Literature References
PubMed ID Title Journal Year
22000013 Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs

Weiss, D, Karreth, F, Tan, SM, Di Cunto, F, Rigoutsos, I, Provero, P, Ala, U, Kats, L, Poliseno, L, Tay, Y, Pandolfi, PP, Lieberman, J, Salmena, L

Cell 2011
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as an event of
Authored
Salmena, L  (2016-08-11)
Orlic-Milacic, M  (2016-11-03)
Carracedo, A  (2016-08-11)
Created
Orlic-Milacic, M  (2016-11-15)
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