miR-20 microRNAs bind VAPA mRNA

Stable Identifier
R-HSA-8948621
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
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miR-20 microRNAs bind VAPA mRNA
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MicroRNAs miR-20a and miR-20b bind the VAPA mRNA. VAPA mRNA acts as a competing endogenous RNA (ceRNA) for PTEN, preventing binding of miR-20 microRNAs to PTEN mRNA and PTEN downregulation (Tay et al. 2011).

Literature References
PubMed ID Title Journal Year
22000013 Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs

Tay, Y, Kats, L, Salmena, L, Weiss, D, Tan, SM, Ala, U, Karreth, F, Poliseno, L, Provero, P, Di Cunto, F, Lieberman, J, Rigoutsos, I, Pandolfi, PP

Cell 2011
Participants
Input
Output
Participant Of
hasEvent
Authored
Orlic-Milacic, M  (2016-11-03)
Carracedo, A  (2016-08-11)
Salmena, L  (2016-08-11)
Created
Orlic-Milacic, M  (2016-11-14)