miR-19a microRNA binds VAPA mRNA

Stable Identifier
R-HSA-8948594
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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miR-19a microRNA binds VAPA mRNA
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MicroRNA miR-19a binds the VAPA mRNA. VAPA mRNA acts as a competing endogenous RNA (ceRNA) for PTEN, preventing binding of miR-19a microRNA to PTEN mRNA and PTEN downregulation (Tay et al. 2011).

Literature References
PubMed ID Title Journal Year
22000013 Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs

Weiss, D, Karreth, F, Tan, SM, Di Cunto, F, Rigoutsos, I, Provero, P, Ala, U, Kats, L, Poliseno, L, Tay, Y, Pandolfi, PP, Lieberman, J, Salmena, L

Cell 2011
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as an event of
Authored
Salmena, L  (2016-08-11)
Orlic-Milacic, M  (2016-11-03)
Carracedo, A  (2016-08-11)
Created
Orlic-Milacic, M  (2016-11-15)
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