PLOD3 binds Lysyl hydroxylated collagen propeptides

Stable Identifier
R-HSA-8948219
Type
Reaction [binding]
Species
Homo sapiens
Compartment
endoplasmic reticulum lumen, endoplasmic reticulum membrane
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
PLOD3 binds Lysyl hydroxylated collagen propeptides
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The ER membrane-associated enzyme PLOD3 has collagen galactosyltransferase activity (Heikkinen et al. 2000, Wang et al. 2002), though whether it physiologically relevant has been questioned (Schegg et al. 2009).

Literature References
PubMed ID Title Journal Year
12475640 The third activity for lysyl hydroxylase 3: galactosylation of hydroxylysyl residues in collagens in vitro

Myllylä, R, Luosujärvi, H, Uitto, L, Wang, C, Risteli, M, Heikkinen, J

Matrix Biol 2002
10934207 Lysyl hydroxylase 3 is a multifunctional protein possessing collagen glucosyltransferase activity

Myllylä, R, Wang, C, Risteli, M, Rossi, M, Heikkinen, J, Valtavaara, M, Latvala, J

J Biol Chem 2000
Participants
Input
Output
Participates
as an event of
Orthologous Events
PLOD3 binds Lysyl hydroxylated collagen propeptides (Bos taurus)
PLOD3 binds Lysyl hydroxylated collagen propeptides (Canis familiaris)
PLOD3 binds Lysyl hydroxylated collagen propeptides (Danio rerio)
PLOD3 binds Lysyl hydroxylated collagen propeptides (Mus musculus)
PLOD3 binds Lysyl hydroxylated collagen propeptides (Rattus norvegicus)
PLOD3 binds Lysyl hydroxylated collagen propeptides (Sus scrofa)
PLOD3 binds Lysyl hydroxylated collagen propeptides (Xenopus tropicalis)
Authored
Jupe, S  (2012-04-11)
Reviewed
Canty-Laird, EG  (2012-05-24)
Created
Jupe, S  (2016-11-11)
Cite Us!