Reactome | CDKN1C [nucleoplasm]

Stable Identifier

R-HSA-8948130

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2, Kip2

Locations in the PathwayBrowser

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Disease (Homo sapiens)

External Reference Information

External Reference

UniProt:P49918 CDKN1C

Gene Names

CDKN1C, KIP2

Chain

chain:1-316

Reference Genes

COSMIC (genes):CDKN1C CDKN1C

dbSNP Gene:1028 CDKN1C

ENSEMBL:ENSG00000129757 CDKN1C

Participates

as a candidate of

Other forms of this molecule

p-Y91-CDKN1C [cytosol]

CDKN1C [cytosol]

Inferred To

CDKN1C [nucleoplasm] (Bos taurus)

CDKN1C [nucleoplasm] (Canis familiaris)

CDKN1C [nucleoplasm] (Sus scrofa)

Cdkn1c [nucleoplasm] (Mus musculus)

Cdkn1c [nucleoplasm] (Rattus norvegicus)

dap [nucleoplasm] (Drosophila melanogaster)

cdkn1ca [nucleoplasm] (Danio rerio)

cdknx [nucleoplasm] (Xenopus tropicalis)

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P24941 CDK2	5	p-T160-CDK2 [nucleoplasm] (R-HSA-187967) CDK2 [nucleoplasm] (R-HSA-68365) CDK2 [cytosol] (R-HSA-157440) p-CDK2 [nucleoplasm] (R-HSA-68370) p-Y15-CDK2 [nucleoplasm] (R-HSA-187905)	0.643	5
UniProt:P11802 CDK4	3	p-T172-CDK4 [nucleoplasm] (R-HSA-113830) CDK4 [nucleoplasm] (R-HSA-113843) CDK4 [cytosol] (R-HSA-68330)	0.564	2
UniProt:P24385 CCND1	4	CCND1 [nucleoplasm] (R-HSA-113832) CCND1 [cytosol] (R-HSA-68328) p-T286-CCND1 [cytosol] (R-HSA-75813) p-T286-CCND1 [nucleoplasm] (R-HSA-75811)	0.527	3
UniProt:P30281 CCND3	2	CCND3 [nucleoplasm] (R-HSA-113835) CCND3 [cytosol] (R-HSA-68333)	0.527	3
UniProt:P33993 MCM7	1	MCM7 [nucleoplasm] (R-HSA-68555)	0.527	2