Reactome | p-ATG13 [endoplasmic reticulum membrane]

p-ATG13 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-8948049

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Autophagy-related protein 13, ATG13_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O75143 ATG13

Gene Names

ATG13, KIAA0652

Chain

chain:1-517

Reference Genes

BioGPS Gene:9776 O751432

COSMIC (genes):ATG13 ATG13

CTD Gene:9776 O751432

dbSNP Gene:9776 O751432

ENSEMBL:ENSG00000175224 ATG13

HGNC:29091 O751432

KEGG:hsa:9776 O751432

Monarch:9776 O751432

NCBI Gene:9776 O751432

OMIM:615088 O751432

UCSC:O75143 O751432

Reference Transcript

Participates

as a component of

p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [endoplasmic reticulum membrane] (Homo sapiens)

Other forms of this molecule

p-ATG13 [cytosol]

ATG13 [cytosol]

Inferred To

phospho-Atg13 [endoplasmic reticulum membrane] (Drosophila melanogaster)

phospho-Atg13 [endoplasmic reticulum membrane] (Mus musculus)

phospho-Atg13 [endoplasmic reticulum membrane] (Rattus norvegicus)

phospho-atg-13 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

phospho-ATG13 [endoplasmic reticulum membrane] (Bos taurus)

phospho-ATG13 [endoplasmic reticulum membrane] (Canis familiaris)

phospho-ATG13 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

phospho-ATG13 [endoplasmic reticulum membrane] (Sus scrofa)

phospho-p-ATG13 [endoplasmic reticulum membrane] (Dictyostelium discoideum)

phospho-p-ATG13 [endoplasmic reticulum membrane] (Gallus gallus)

phospho-atg13 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

phospho-atg13 [endoplasmic reticulum membrane] (Xenopus tropicalis)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Cross References

RefSeq

NP_001333240.1, NP_001333241.1, NP_001333260.1, NP_001333282.1, XP_006718459.1, NP_001333261.1, NP_001333283.1, NP_001333248.1, NP_001333249.1, XP_011518798.1, NP_001333245.1, NP_001136145.1, XP_011518795.1, NP_001333253.1, NP_001333257.1, NP_001333244.1, NP_001333243.1, NP_001333254.1, NP_001333258.1, NP_001333271.1, NP_001333250.1, NP_001333275.1, NP_001333279.1, NP_001333242.1, NP_001333280.1, NP_001333281.1, XP_016874092.1, XP_016874088.1, XP_011518801.1, XP_016874096.1, NP_001192048.1, XP_005253323.1, NP_001192050.1, XP_005253322.1, NP_001192049.1, NP_001333278.1, NP_001333251.1, NP_001333259.1, NP_001333256.1, NP_001333277.1, NP_001333255.1, NP_001192051.1, XP_005253325.1, NP_001333252.1, NP_001333273.1, NP_055556.2

OpenTargets

ENSG00000175224

ENSEMBL

ENSP00000433543, ENSP00000433756, ENSP00000432412, ENSP00000431974, ENST00000528494, ENSG00000175224, ENSP00000352500, ENSP00000434390, ENST00000530500, ENST00000529655, ENSP00000507809, ENST00000526508, ENST00000683050, ENST00000359513, ENST00000524625

HPA

ENSG00000175224-ATG13

GeneCards

ATG13

PRO

O75143

Pharos - Targets

O75143

GlyGen

O75143

PDB

9C82, 3WAP, 5XV4, 5XV3, 3WAO, 3WAN, 8SQZ, 8DO8, 5XV1, 6HYN, 5C50, 5XV6, 8SOI, 8SRM, 5XUY

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75385 ULK1	7	ULK1 [cytosol] (R-HSA-1632847) ULK1 [mitochondrial outer membrane] (R-HSA-8948145) p-T180,S317,S467,S556,S638,T575-ULK1 [endoplasmic reticulum membrane] (R-HSA-8948047) p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol] (R-HSA-5675858) p-S317,467,556,638,T575-ULK1 [cytosol] (R-HSA-5673747) p-S758-ULK1 [cytosol] (R-HSA-5672131) ULK1 [recycling endosome] (R-HSA-8854761)	0.937	15
UniProt:Q9GZQ8 MAP1LC3B	3	MAP1LC3B [cytosol] (R-HSA-5205651) MAP1LC3B(2-121) [cytosol] (R-HSA-5682674) MAP1LC3B [autophagosome membrane] (R-HSA-5683641)	0.734	5
UniProt:Q676U5 ATG16L1	1	ATG16L1 [cytosol] (R-HSA-5671734)	0.527	2
UniProt:Q9H1Y0 ATG5	3	ATG5 [phagocytic vesicle membrane] (R-HSA-5205636) GlyK130-ATG5 [cytosol] (R-HSA-5683582) ATG5 [cytosol] (R-HSA-936010)	0.527	2

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