Reactome | RB1CC1 [endoplasmic reticulum membrane]

RB1CC1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-8948046

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

RB1-inducible coiled-coil protein 1, RBCC1_HUMAN, FAK family kinase-interacting protein of 200 kDa, FIP200

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8TDY2 RB1CC1

Gene Names

RB1CC1, KIAA0203, RBICC

Chain

chain:1-1594

Reference Genes

BioGPS Gene:9821 RB1CC1

COSMIC (genes):RB1CC1 RB1CC1

CTD Gene:9821 RB1CC1

dbSNP Gene:9821 RB1CC1

ENSEMBL:ENSG00000023287 RB1CC1

HGNC:15574 RB1CC1

KEGG:hsa:9821 RB1CC1

Monarch:9821 RB1CC1

NCBI Gene:9821 RB1CC1

OMIM:606837 RB1CC1

UCSC:Q8TDY2 RB1CC1

Reference Transcript

Other Identifiers

11743480_s_at

11743481_at

17077135

202033_PM_s_at

202033_s_at

202034_PM_x_at

202034_x_at

3135190

3135191

3135192

3135193

3135194

3135195

3135196

3135199

3135202

3135204

3135205

3135206

3135207

3135208

3135209

3135210

3135211

3135213

3135221

3135222

3135223

3135224

3135225

3135226

3135227

3135228

3135229

3135230

3135231

3135232

3135233

3135236

3135237

3135238

3135239

3135240

3135241

3135242

3135243

3135244

3135250

3135251

34875_r_at

8150757

9821

A_23_P9056

D86958_at

GE57364

GO:0000045

GO:0000407

GO:0000421

GO:0000422

GO:0001889

GO:0002376

GO:0005515

GO:0005634

GO:0005737

GO:0005764

GO:0005773

GO:0005789

GO:0005829

GO:0005975

GO:0006091

GO:0006914

GO:0006915

GO:0007005

GO:0007507

GO:0008285

GO:0010508

GO:0012501

GO:0019901

GO:0030242

GO:0031965

GO:0034045

GO:0034517

GO:0034727

GO:0043066

GO:0043226

GO:0043495

GO:0045087

GO:0045793

GO:0046330

GO:0048856

GO:0051607

GO:0060090

GO:0061709

GO:0061723

GO:0097191

GO:0098542

GO:1903059

GO:1990316

GO:2001237

HMNXSV003047435

Hs.50421.0.S1_3p_a_at

ILMN_1736796

PH_hs_0022683

TC08001210.hg

Z35085_s_at

g7661991_3p_a_at

Participates

as a component of

p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [endoplasmic reticulum membrane] (Homo sapiens)

Other forms of this molecule

p-RB1CC1 [cytosol]

RB1CC1 [cytosol]

Inferred To

Rb1cc1 [endoplasmic reticulum membrane] (Mus musculus)

Rb1cc1 [endoplasmic reticulum membrane] (Rattus norvegicus)

ATG11 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

taf1 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

rb1cc1 [endoplasmic reticulum membrane] (Xenopus tropicalis)

RB1CC1 [endoplasmic reticulum membrane] (Bos taurus)

RB1CC1 [endoplasmic reticulum membrane] (Canis familiaris)

RB1CC1 [endoplasmic reticulum membrane] (Gallus gallus)

RB1CC1 [endoplasmic reticulum membrane] (Sus scrofa)

Ghost homologue of RB1CC1 [endoplasmic reticulum membrane] (Dictyostelium discoideum)

Atg17 [endoplasmic reticulum membrane] (Drosophila melanogaster)

epg-7 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

Cross References

RefSeq

XP_011515945.1, NP_055596.3, XP_016869596.1, NP_001077086.1

OpenTargets

ENSG00000023287

ENSEMBL

ENSP00000396067, ENSP00000025008, ENST00000435644, ENST00000025008

HPA

ENSG00000023287-RB1CC1

PRO

Q8TDY2

Pharos - Targets

Q8TDY2

GlyGen

Q8TDY2

PDB

6GMA, 8SQZ, 8SRM, 7CZM, 8SOI, 7EAA, 6DCE, 7EA2, 7CZG, 8SRQ, 7D0E

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75385 ULK1	7	ULK1 [cytosol] (R-HSA-1632847) ULK1 [mitochondrial outer membrane] (R-HSA-8948145) p-T180,S317,S467,S556,S638,T575-ULK1 [endoplasmic reticulum membrane] (R-HSA-8948047) p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol] (R-HSA-5675858) p-S317,467,556,638,T575-ULK1 [cytosol] (R-HSA-5673747) p-S758-ULK1 [cytosol] (R-HSA-5672131) ULK1 [recycling endosome] (R-HSA-8854761)	0.906	13
UniProt:Q676U5 ATG16L1	1	ATG16L1 [cytosol] (R-HSA-5671734)	0.748	6
UniProt:Q9H1Y0 ATG5	3	ATG5 [phagocytic vesicle membrane] (R-HSA-5205636) GlyK130-ATG5 [cytosol] (R-HSA-5683582) ATG5 [cytosol] (R-HSA-936010)	0.623	3
UniProt:O94817 ATG12	2	ATG12 [phagocytic vesicle membrane] (R-HSA-5205625) ATG12 [cytosol] (R-HSA-936011)	0.564	2
UniProt:Q9NYA4 MTMR4	2	MTMR4 [cytosol] (R-HSA-1604658) MTMR4 [early endosome membrane] (R-HSA-2187404)	0.483	2
UniProt:Q9UHD2 TBK1	5	p-S172-TBK1 [cytosol] (R-HSA-168379) TBK1 [cytosol] (R-HSA-166267) K63polyUb-K30,K401-TBK1 [cytosol] (R-HSA-9730430) p-TBK1 [cytosol] (R-HSA-9008705) pS-172,K48polyUb-TBK1 [cytosol] (R-HSA-3249397)	0.483	2