FGR binds LDL:LRP8

Stable Identifier
R-HSA-8948034
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane, cytosol
ReviewStatus
5/5
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FGR binds LDL:LRP8
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Tyrosine phosphorylation of LDL:LRP8 is mediated by the Src-family kinase FGR, based on a correlation of increased LRP8 phosphorylation in LDL-stimulated platelets and a transient increased co-precipitation of FGR and LRP8 upon LDL stimulation.

Literature References
PubMed ID Title Journal Year
15459198 Binding of low density lipoprotein to platelet apolipoprotein E receptor 2' results in phosphorylation of p38MAPK

Akkerman, JW, Gorter, G, Korporaal, SJ, Strasser, V, Lenting, PJ, Bezemer, M, Nimpf, J, van Eck, M, Relou, IA, van Berkel, TJ

J Biol Chem 2004
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Orthologous Events
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FGR binds LDL:LRP8 (Rattus norvegicus)
FGR binds LDL:LRP8 (Sus scrofa)
Authored
Akkerman, JW  (2009-09-04)
Reviewed
Kunapuli, SP  (2010-06-07)
Created
Jupe, S  (2016-11-08)
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