hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb

Stable Identifier
R-HSA-8948015
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Activated ubiquitin is transferred to a heterodimeric E2 conjugating enzyme UBE2N (Ubc13) and UBEE2V1 (Uev1A) forming an E2-Ub thioester.

Literature References
PubMed ID Title Journal Year
17135271 Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation

Lamothe, B, Besse, A, Campos, AD, Webster, WK, Wu, H, Darnay, BG

J Biol Chem 2007
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