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SCUBE3 [plasma membrane]
Stable Identifier
R-HSA-8943884
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Signal peptide, CUB and EGF-like domain-containing protein 3, SCUB3_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Degradation of the extracellular matrix (Homo sapiens)
MMP2, MMP9 cleave SCUBE3 (Homo sapiens)
SCUBE3 [plasma membrane] (Homo sapiens)
SCUBE1, SCUBE3 oligomerize (Homo sapiens)
SCUBE1,SCUBE3 [plasma membrane] (Homo sapiens)
SCUBE3 [plasma membrane] (Homo sapiens)
SCUBE1,SCUBE3 polymer, SCUBE3 polymer [plasma membrane] (Homo sapiens)
SCUBE1,SCUBE3 polymer [plasma membrane] (Homo sapiens)
SCUBE1,SCUBE3 [plasma membrane] (Homo sapiens)
SCUBE3 [plasma membrane] (Homo sapiens)
SCUBE3 polymer [plasma membrane] (Homo sapiens)
SCUBE3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8IX30 SCUBE3
Gene Names
SCUBE3, CEGF3
Chain
signal peptide:1-20, chain:21-993
Reference Genes
BioGPS Gene:222663 SCUBE3
COSMIC (genes):SCUBE3 SCUBE3
CTD Gene:222663 SCUBE3
dbSNP Gene:222663 SCUBE3
ENSEMBL:ENSG00000146197 SCUBE3
HGNC:13655 SCUBE3
Monarch:222663 SCUBE3
NCBI Gene:222663 SCUBE3
OMIM:614708 SCUBE3
UCSC:Q8IX30 SCUBE3
Reference Transcript
RefSeq:NM_152753.3 SCUBE3
RefSeq:NM_001303136.1 SCUBE3
RefSeq:XM_005248943.1 SCUBE3
Other Identifiers
11728431_a_at
11755019_s_at
17007738
222663
228407_PM_at
228407_at
230290_PM_at
230290_at
2904486
2904487
2904489
2904490
2904491
2904493
2904494
2904497
2904498
2904499
2904500
2904502
2904504
2904505
2904506
2904509
2904510
2904511
2904514
2904515
2904516
2904518
2904521
2904523
2904524
2904525
2904526
2904527
46728_at
46729_g_at
74255_at
8118890
90121_at
A_14_P133369
A_24_P943894
GE833208
GO:0005509
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0007165
GO:0009986
GO:0030513
GO:0036122
GO:0042802
GO:0045669
GO:0070700
HMNXSV003051507
Hs.128151.0.A1_3p_at
Hs.44165.0.A1_3p_at
ILMN_1659359
PH_hs_0022408
TC06000511.hg
Participates
as a repeated unit of
SCUBE3 polymer [plasma membrane] (Homo sapiens)
as a member of
SCUBE1,SCUBE3 [plasma membrane] (Homo sapiens)
as an input of
MMP2, MMP9 cleave SCUBE3 (Homo sapiens)
Other forms of this molecule
SCUBE3(?-993) [plasma membrane]
SCUBE3(21-?) [plasma membrane]
Inferred To
SCUBE3 [plasma membrane]
(Bos taurus)
SCUBE3 [plasma membrane]
(Canis familiaris)
SCUBE3 [plasma membrane]
(Gallus gallus)
SCUBE3 [plasma membrane]
(Plasmodium falciparum)
SCUBE3 [plasma membrane]
(Sus scrofa)
Scube3 [plasma membrane]
(Mus musculus)
Scube3 [plasma membrane]
(Rattus norvegicus)
Cross References
ENSEMBL
ENSP00000274938
,
ENST00000274938
OpenTargets
ENSG00000146197
HPA
ENSG00000146197-SCUBE3
PRO
Q8IX30
Pharos - Targets
Q8IX30
GlyGen
Q8IX30
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P37173 TGFBR2
9
TGFBR2 [plasma membrane]
(R-HSA-170842)
NEDD8-K556,K567-TGFBR2 [plasma membrane]
(R-HSA-4332222)
TGFBR2 K128Sfs*35 [cytosol]
(R-HSA-3642166)
TGFBR2 K128Afs*3 [cytosol]
(R-HSA-3642173)
TGFBR2 R528C [plasma membrane]
(R-HSA-3640899)
TGFBR2 R528H [plasma membrane]
(R-HSA-3640894)
TGFBR2 D522N [plasma membrane]
(R-HSA-3640907)
TGFBR2 E526Q [plasma membrane]
(R-HSA-3645770)
TGFBR2 Y470D [plasma membrane]
(R-HSA-3640905)
0.632
6
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