MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene [nucleoplasm]

Stable Identifier
Homo sapiens
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
21289308 Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins

Yoshimi, A, Goyama, S, Watanabe-Okochi, N, Yoshiki, Y, Nannya, Y, Nitta, E, Arai, S, Sato, T, Shimabe, M, Nakagawa, M, Imai, Y, Kitamura, T, Kurokawa, M

Blood 2011
19884659 The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells

Song, LB, Li, J, Liao, WT, Feng, Y, Yu, CP, Hu, LJ, Kong, QL, Xu, LH, Zhang, X, Liu, WL, Li, MZ, Zhang, L, Kang, TB, Fu, LW, Huang, WL, Xia, YF, Tsao, SW, Li, M, Band, V, Band, H, Shi, QH, Zeng, YX, Zeng, MS

J. Clin. Invest. 2009
This entity regulates
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