MECOM (EVI1) binds the PTEN gene promoter

Stable Identifier
R-HSA-8943811
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The transcription factor MECOM (EVI1) binds the promoter of the PTEN gene (Yoshimi et al. 2011).

Literature References
PubMed ID Title Journal Year
21289308 Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins

Yoshimi, A, Goyama, S, Watanabe-Okochi, N, Yoshiki, Y, Nannya, Y, Nitta, E, Arai, S, Sato, T, Shimabe, M, Nakagawa, M, Imai, Y, Kitamura, T, Kurokawa, M

Blood 2011
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