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SALL4:PTEN gene
Stable Identifier
R-HSA-8943729
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
PIP3 activates AKT signaling (Homo sapiens)
PTEN Regulation (Homo sapiens)
Regulation of PTEN gene transcription (Homo sapiens)
SALL4 binds the PTEN gene promoter (Homo sapiens)
SALL4:PTEN gene [nucleoplasm] (Homo sapiens)
SALL4 recruits NuRD to PTEN gene (Homo sapiens)
SALL4:PTEN gene [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
19440552
Stem cell factor SALL4 represses the transcriptions of PTEN and SALL1 through an epigenetic repressor complex
PLoS One
2009
18487508
SALL4 is a key regulator of survival and apoptosis in human leukemic cells
Blood
2008
Participants
components
PTEN gene [nucleoplasm] (Homo sapiens)
SALL4 [nucleoplasm] (Homo sapiens)
Participant Of
input
SALL4 recruits NuRD to PTEN gene
output
SALL4 binds the PTEN gene promoter
Inferred To
SALL4:PTEN gene [nucleoplasm] (Bos taurus)
SALL4:PTEN gene [nucleoplasm] (Caenorhabditis elegans)
SALL4:PTEN gene [nucleoplasm] (Canis familiaris)
SALL4:PTEN gene [nucleoplasm] (Danio rerio)
SALL4:PTEN gene [nucleoplasm] (Drosophila melanogaster)
SALL4:PTEN gene [nucleoplasm] (Gallus gallus)
SALL4:PTEN gene [nucleoplasm] (Mus musculus)
SALL4:PTEN gene [nucleoplasm] (Rattus norvegicus)
SALL4:PTEN gene [nucleoplasm] (Sus scrofa)
SALL4:PTEN gene [nucleoplasm] (Taeniopygia guttata)
SALL4:PTEN gene [nucleoplasm] (Xenopus tropicalis)
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