Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
TMEM129 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-8943134
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
E3 ubiquitin-protein ligase TM129 ecNumber6.3.2.-/ecNumber, TM129_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Protein ubiquitination (Homo sapiens)
E3 ubiquitin ligases ubiquitinate target proteins (Homo sapiens)
TMEM129 polyubiquitinates HLA (MHC class I heavy chain) bound to cytomegalovirus US11 (Homo sapiens)
TMEM129 [endoplasmic reticulum membrane] (Homo sapiens)
TMEM129:DERL1:VIMP:VCP:UBE2J2 [endoplasmic reticulum membrane] (Homo sapiens)
TMEM129 [endoplasmic reticulum membrane] (Homo sapiens)
US11:HLA:TMEM129:DERL1:VIMP:VCP:Ub:UBE2J2 [endoplasmic reticulum membrane] (Homo sapiens)
TMEM129:DERL1:VIMP:VCP:Ub:UBE2J2 [endoplasmic reticulum membrane] (Homo sapiens)
TMEM129 [endoplasmic reticulum membrane] (Homo sapiens)
US11:HLA binds DERL1:TMEM129:Ub:UBE2J2,UBE2K:VIMP:VCP (Homo sapiens)
TMEM129:DERL1:VIMP:VCP:Ub:UBE2J2 [endoplasmic reticulum membrane] (Homo sapiens)
TMEM129 [endoplasmic reticulum membrane] (Homo sapiens)
US11:HLA:TMEM129:DERL1:VIMP:VCP:Ub:UBE2J2 [endoplasmic reticulum membrane] (Homo sapiens)
TMEM129:DERL1:VIMP:VCP:Ub:UBE2J2 [endoplasmic reticulum membrane] (Homo sapiens)
TMEM129 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:A0AVI4 TMEM129
Gene Names
TMEM129
Chain
chain:1-362
Reference Genes
BioGPS Gene:92305 TMEM129
COSMIC (genes):TMEM129 TMEM129
CTD Gene:92305 TMEM129
dbSNP Gene:92305 TMEM129
ENSEMBL:ENSG00000168936 TMEM129
ENSEMBL_homo_sapiens_GENE:ENSG00000168936.12 TMEM129
HGNC:25137 TMEM129
KEGG Gene (Homo sapiens):92305 TMEM129
Monarch:92305 TMEM129
NCBI Gene:92305 TMEM129
OMIM:615975 TMEM129
UCSC:A0AVI4 TMEM129
Reference Transcript
RefSeq:NM_138385.3 TMEM129
RefSeq:NM_001127266.1 TMEM129
Other Identifiers
11717495_a_at
11747642_a_at
11749547_a_at
11755330_a_at
16973588
225587_PM_at
225587_at
225588_PM_s_at
225588_s_at
2757343
2757344
2757346
2757348
2757349
2757350
2757351
2757352
2757354
2757356
2757358
2757359
2757360
48679_at
48680_at
8098916
89179_at
92305
A_23_P354175
GO:0000209
GO:0003824
GO:0005515
GO:0005783
GO:0005789
GO:0006511
GO:0006886
GO:0006986
GO:0016020
GO:0016567
GO:0016740
GO:0030163
GO:0030970
GO:0036211
GO:0036503
GO:0043226
GO:0046872
GO:0061630
GO:0140096
HMNXSV003003908
Hs.300697.2.A1_3p_at
ILMN_1663033
PH_hs_0033396
TC04000969.hg
Participates
as a component of
TMEM129:DERL1:VIMP:VCP:UBE2J2 [endoplasmic reticulum membrane] (Homo sapiens)
TMEM129:DERL1:VIMP:VCP:Ub:UBE2J2 [endoplasmic reticulum membrane] (Homo sapiens)
Cross References
RefSeq
NP_612394.1
,
NP_001120738.1
OpenTargets
ENSG00000168936
IntEnz
2.3.2.27
GeneCards
A0AVI4
HPA
ENSG00000168936-TMEM129
Ensembl
ENSP00000305243
,
ENST00000382936
,
ENST00000303277
,
ENSP00000372394
,
ENSG00000168936
PRO
A0AVI4
Pharos - Targets
A0AVI4
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text